Results 71 to 80 of about 59,093 (301)

The Opioid Crisis in Rural and Small Town America [PDF]

, 2018
In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas.
Monnat, Shannon M, Rigg, Khary K
core   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri, Bart Morlion, Vidhu Sood Sethi, Mary Cardosa, Oscar Della Pasqua, Pranab Kalita   +5 more
wiley   +1 more source

Unemployment and opioid overdose death patterns in the United States from 2017 to 2019

Interdisciplinary Journal of Epidemiology and Public Health
Introduction: Unemployment has been linked to increased opioid-related harms such as opioid overdose deaths. Identifying hotspots and coldspots across the United States (US) can be crucial to understanding health resources and leveraging strategies ...
Rana Khafagy, Saranya Naraentheraraja, Aranee Sathiyamoorthy   +2 more
doaj   +1 more source

A conceptual model for understanding post-release opioid-related overdose risk

Addiction Science & Clinical Practice, 2019
Post-release opioid-related overdose mortality is the leading cause of death among people released from jails or prisons (PRJP). Informed by the proximate determinants framework, this paper presents the Post-Release Opioid-Related Overdose Risk Model. It
Paul J. Joudrey, Maria R. Khan, Emily A. Wang, Joy D. Scheidell, E. Jennifer Edelman, D. Keith McInnes, Aaron D. Fox   +6 more
doaj   +1 more source

Medication-assisted treatment and opioid use response to opioid overdose sentinel events [PDF]

, 2017
Introduction A nonfatal overdose due to opioids can be viewed as a failure to adequately treat addiction or as an opportunity to start or improve treatment for opioid use disorder (OUD).
Frazier, Winfred
core  

Association of Opioid Overdose With Opioid Prescriptions to Family Members [PDF]

JAMA Internal Medicine, 2019
Prescription opioid misuse is a public health problem that leads to overdose. Although existing interventions focus on limiting prescribing to patients at high risk, individuals may still access prescription opioids dispensed to family members.To determine whether opioid prescriptions to family members were associated with overdose for individuals who ...
Nazleen F. Khan, Joshua J. Gagne, Brian T. Bateman, Joan Landon   +3 more
openaire   +3 more sources

Volatilome and Antinociceptive Activity of the Traditional Preparation and Compounds from Ageratina grandifolia (Regel) R.M. King & H. Rob.

Chemistry &Biodiversity, EarlyView.
Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol (4)], tested at 10, 31.6, and 100 mg/kg, intragastrically administered, showed a significant antinociceptive effect in both phases of the formalin test in mice ...
José Alberto Gutiérrez‐González, Isabel Rivero‐Cruz, José L. Villaseñor, Gabriela García‐Marín, Ana Laura Martínez, Rachel Mata   +5 more
wiley   +1 more source

Identification of the Novel Synthetic Opioid N‐Pyrrolidino Isotonitazene at an Australian Drug Checking Service

Drug Testing and Analysis, EarlyView.
Close collaboration between an Australian drug checking service and an affiliated university laboratory identifies and characterises the novel synthetic opioid N‐pyrrolidino isotonitazene in an expected oxycodone sample presented by a member of the public.
Blake Curtis, Douglas J. Lawes, David Caldicott, Malcolm D. McLeod   +3 more
wiley   +1 more source

Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne

Drug Testing and Analysis, EarlyView.
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku, Anna Pelander, Antti Jylhä, Ilkka Ojanperä   +3 more
wiley   +1 more source

Collateral Damage: Neurological Correlates of Non-Fatal Overdose in the Era of Fentanyl-Xylazine

Neuroscience Insights
Non-fatal opioid overdoses are associated with significant morbidity. Hypoxic brain injury caused by opioid-induced respiratory depression is a key mechanism of such morbidity. For example, reports describe an amnestic syndrome in opioid users associated
Dustin R Todaro, Nora D Volkow, Daniel D Langleben, Zhenhao Shi, Corinde E Wiers   +4 more
doaj   +1 more source