Results 71 to 80 of about 63,125 (287)
Naloxone Administration Route in Opioid Overdose: A Review of Vermont EMS Data [PDF]
, 2017 Objective: Emergency Medical System (EMS) personnel administer the direct opioid antagonist naloxone in cases of opioid overdose via intramuscular (IM), intravenous (IV), subcutaneous (SQ), intraosseous (IO), or intranasal (IN) routes. Some early studies
LaMonda, Chris, MPH +4 more
core +1 more source
Firsthand Opiates Abuse on Social Media: Monitoring Geospatial Patterns of Interest Through a Digital Cohort [PDF]
, 2019 In the last decade drug overdose deaths reached staggering proportions in the US. Besides the raw yearly deaths count that is worrisome per se, an alarming picture comes from the steep acceleration of such rate that increased by 21% from 2015 to 2016 ...
Bajardi, Paolo +2 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co‐administration with CYP3A4‐inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the clinical impact of these interactions is unknown.
Tony Antoniou +7 more
wiley +1 more source
Medication-assisted treatment and opioid use response to opioid overdose sentinel events [PDF]
, 2017 Introduction A nonfatal overdose due to opioids can be viewed as a failure to adequately treat addiction or as an opportunity to start or improve treatment for opioid use disorder (OUD).
Frazier, Winfred
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Drug Critical Limits for Urgent Physician Notification
Clinical Pharmacology &Therapeutics, EarlyView.Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang +3 more
wiley +1 more source
Synthetic opioids have disrupted conventional wisdom for treating opioid overdose
Drug and Alcohol Dependence ReportsMore than 90 % of opioid overdose deaths in North America are now caused by synthetic opioids, and while they are not as prevalent in the European illicit drug market, there are indications that they may become so in the near future.
Phil Skolnick +2 more
doaj +1 more source
Harm reduction among injecting drug users - evidence of effectiveness [PDF]
, 2010 This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Goldberg, David +5 more
core +1 more source
Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose
Drug Testing and Analysis, EarlyView.A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek +3 more
wiley +1 more source
Health Economics, EarlyView.ABSTRACT Some patients prescribed opioid pills fail to properly dispose of their unused pills, posing a risk for others. We report results from a pre‐registered field experiment testing whether behaviorally informed reminder cards increase participation in a financial incentive program for returning unused opioid pills among U.S. Veterans.
Mattie Toma +7 more
wiley +1 more source
The Prescription Opioid Epidemic: an Evidence-Based Approach [PDF]
, 2015 A group of experts, led by researchers at the Johns Hopkins Bloomberg School of Public Health, issued this report aimed at stemming the prescription opioid epidemic, a crisis that kills an average of 44 people a day in the U.S.
G. Caleb Alexander, Shannon Frattaroli
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