Results 141 to 150 of about 30,638 (285)

The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin [PDF]

, 1995
L Chen, Yunjuan Gu, LY Huang
openalex   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

Annals of Neurology, Volume 98, Issue 4, Page 777-787, October 2025.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim, Manyoel Lim, Thiago D. Nascimento, Frank Porreca, Robert A. Koeppe, Nouchine Hadjikhani, Alexandre F. DaSilva   +6 more
wiley   +1 more source

Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia. [PDF]

Cell Biosci, 2020
Lai Z, Gu L, Yu L, Chen H, Yu Z, Zhang C, Xu X, Zhang M, Zhang M, Ma M, Zhao Z, Zhang J.   +11 more
europepmc   +1 more source

Opioid Peptide Gene Expression in the Primary Hereditary Cardiomyopathy of the Syrian Hamster [PDF]

, 1997
Carlo Ventura, Gianfranco Pintus
openalex   +1 more source

Genetic Basis of the Negative Response to the Use of Triptans for the Treatment of Migraine—A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 10, October 2025.
To systematize the genetic basis correctly associated with nonresponse to triptan, we revised etiological studies on Web of Science, Embase, and PubMed until 2023. We found that only polymorphisms in the SLC6A4, 5‐HT1B, and COMT genes have a stronger association with this condition. More robust studies are needed to increase this certainty.
Victoria Gomes Andreata, Ruan Pablo Duarte Freitas, Jéssica da Silva Nascimento, Patrícia Sodré Araújo, Felipe Eustáquio dos Santos Guedes, João Vítor Benjamim Pires, Narel Moita Carneiro Nogueira Falcão, Natasha da Silva Leitão, Alcylene Carla de Jesus dos Santos, Ana Patrícia Pascoal Queiroz, Astria Ferrão Dias Gonzales, Maica Matos Leão, Emília Katiane Embiruçu de Araújo Leão, Juliana Côrtes Freitas, Acássia Benjamim Leal Pires   +14 more
wiley   +1 more source

Influences of analgesics on the opioid peptide system in the rat incisor pulp

, 1986
Masato Kuroi, Huei-Ling Chang, Tomoaki Kudo, Reizo Inoki   +3 more
openalex   +1 more source

Endogenous Opioid Peptides Contribute to Suckling-Induced Prolactin Release by Suppressing Tyrosine Hydroxylase Activity and Messenger Ribonucleic Acid Levels in Tuberoinfundibular Dopaminergic Neurons* [PDF]

, 1998
Lydia A. Arbogast, James L. Voogt
openalex   +1 more source

Orexin Deficiency in Narcolepsy: Molecular Mechanisms, Clinical Phenotypes, and Emerging Therapeutic Frontiers

Brain and Behavior, Volume 15, Issue 10, October 2025.
Orexin deficiency drives narcolepsy Type 1, leading to excessive daytime sleepiness, cataplexy, and REM intrusions. This review highlights recent advances (2023–2025) in molecular mechanisms, diagnostics, and emerging orexin‐targeted therapies with the potential for disease modification.
Rameesha Rauf, Salwa Asif, Abdallah AlSaafeen, Kaviprada Geathaa Dhantapaani, Maryam Muhammad Nadeem, Zohra Kamran Rao, Aliya Shaju Shahul Hameed, Karthik Chintharala, Muhammad Faheem Anwar, Asad Ali Ahmed Cheema   +9 more
wiley   +1 more source

Conformational Plasticity Enhances the Brain Penetration of a Metabolically Stable, Dual-Functional Opioid-Peptide CycloAnt. [PDF]

Int J Mol Sci
Li Y, Cotham WE, Eliasof A, Bland K, Walla M, Pellechia PJ, Chen C, Fan D, McLaughlin JP, Liu-Chen LY.   +9 more
europepmc   +1 more source

Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists. [PDF]

Korean J Physiol Pharmacol, 2019
Park JY, Chae S, Kim CS, Kim YJ, Yi HJ, Han E, Joo Y, Hong S, Yun JW, Kim H, Shin KH.   +10 more
europepmc   +1 more source