Results 141 to 150 of about 1,142,563 (307)
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.Wir präsentieren ein photoschaltbares Peptid‐Konjugat, das eine isomerabhängige Selbstassemblierung aufweist: Das planare trans‐Isomer bildet geordnete Nanofibrillen, während das nicht‐planare cis‐Isomer ungeordnete Aggregate ausbildet.
Julian Link +6 more
wiley +1 more source
Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]
, 2004 Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K. +4 more
core +1 more source
Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.We present a photoswitchable peptide conjugate which exhibits isomerism‐dependent self‐assembly: the planar trans‐isomer assembles into well‐ordered nanofibers while the non‐planar cis‐isomer yields disordered aggregates. Our study offers a direct visualization on the effects of structure formation inside living cells.
Julian Link +6 more
wiley +1 more source
Delta Opioid Receptor Activation with Delta Opioid Peptide [d-Ala2, d-Leu5] Enkephalin Contributes to Synaptic Improvement in Rat Hippocampus against Global Ischemia. [PDF]
Cell Transplant, 2021 Zhang G +10 more
europepmc +1 more source
Episodic Ethanol Exposure in Adolescent Rats Causes Residual Alterations in Endogenous Opioid Peptides [PDF]
, 2018 Linnea Granholm +2 more
openalex +1 more source
Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Mutations in GNAO1, the gene encoding Gαo, are associated with a wide range of neurodevelopmental disorders. In this study, we show that Gαo variants linked to the most severe patient phenotypes fail to disengage from activated Gi/o‐coupled GPCRs, thereby blocking GRK‐mediated receptor phosphorylation and internalization.
Yonika A. Larasati +4 more
wiley +1 more source
Functional differences of iodinated obestatin peptides: in vitro metabolic stability profile [PDF]
, 2010 Peptides are small polymers of 50 amino acids, situated between organic molecules and proteins. Most peptides perform a biochemical-physical function and are therefore considered as potential drugs.
De Spiegeleer, Bart +2 more
core +1 more source
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Arthritis Care &Research, Volume 78, Issue 1, Page 154-163, January 2026.Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher +8 more
wiley +1 more source