Mobility-GCN: a human mobility-based graph convolutional network for tracking and analyzing the spatial dynamics of the synthetic opioid crisis in the USA, 2013-2020 [PDF]
arXivSynthetic opioids are the most common drugs involved in drug-involved overdose mortalities in the U.S. The Center for Disease Control and Prevention reported that in 2018, about 70% of all drug overdose deaths involved opioids and 67% of all opioid-involved deaths were accounted for by synthetic opioids.
arxiv
Muscle &Nerve, Volume 71, Issue 5, Page 889-910, May 2025.ABSTRACT Myofascial pain syndrome (MPS) is a chronic regional pain condition characterized by trigger points—hyperirritable spots within taut bands of muscle fibers that cause both localized and referred pain. The pathogenesis, diagnostic criteria, and classification of MPS are still under investigation, which complicates the development of ...
Jeremy P. Steen +2 more
wiley +1 more source
Effects of a new opioid peptide (Tyr-Arg) on lamina V type neurons of the rabbit spinal dorsal horn
, 1979 Masamichi Satoh +3 more
openalex +1 more source
Cocaine Self-administration Regulates Transcription of Opioid Peptide Precursors and Opioid Receptors in Rat Caudate Putamen and Prefrontal Cortex. [PDF]
Neuroscience, 2020 Sun H +4 more
europepmc +1 more source
The Hidden Toll of COVID-19 on Opioid Mortality in Georgia: A Bayesian Excess Opioid Mortality Analysis [PDF]
arXivCOVID-19 has had a large scale negative impact on the health of opioid users exacerbating the health of an already vulnerable population. Critical information on the total impact of COVID-19 on opioid users is unknown due to a lack of comprehensive data on COVID-19 cases, inaccurate diagnostic coding, and lack of data coverage.
arxiv
Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 591-599, May 2025.Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan +5 more
wiley +1 more source
Diet-ODIN: A Novel Framework for Opioid Misuse Detection with Interpretable Dietary Patterns [PDF]
arXivThe opioid crisis has been one of the most critical society concerns in the United States. Although the medication assisted treatment (MAT) is recognized as the most effective treatment for opioid misuse and addiction, the various side effects can trigger opioid relapse.
arxiv
Therapeutic Value of Lactobacillus gasseri 345A in Chronic Constipation
Neurogastroenterology &Motility, Volume 37, Issue 5, May 2025.Preclinical studies show Lactobacillus gasseri to increase intestinal motility and counteract capsaicin‐stimulated transient receptor potential vanilloid 1. In a clinical trial, Lactobacillus gasseri reduced abdominal pain, along with a correlation for increased complete spontaneous bowel movements.
Stefan Roos +7 more
wiley +1 more source
A brief history of opiates, opioid peptides, and opioid receptors. [PDF]
, 1993 M J Brownstein
openalex +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.GPR37 activation alleviates bone cancer pain via peripheral and neuronal mechanisms. NPD1 or ARU targeting GPR37 in macrophages promotes IL‐10 release through β‐arrestin 2 recruitment, thereby inhibiting cancer‐induced osteoclastogenesis. Additionally, GPR37 activation in the DRG and SDH reduces the No. of action potentials and the frequency of sEPSCs,
Kaiyuan Wang +10 more
wiley +1 more source