Results 181 to 190 of about 1,112,203 (348)
The mysterious middlemen making your vision pop: understanding the function of amacrine cells
The Journal of Physiology, EarlyView.Abstract figure legend This review aims to illustrate the diversity and function of amacrine cells in the retina. The diversity of amacrine cell subtypes is depicted based on morphology, stratification and neurotransmitter expression, along with their synaptic connectivity with bipolar and ganglion cells, emphasizing inhibitory and modulatory roles ...
Victor Calbiague‐Garcia +3 more
wiley +1 more source
Opioid peptide precursors in striatum [PDF]
FEBS Letters, 1980 K.M. Metters +3 more
openaire +3 more sources
Advances of Microneedles for Cancer Diagnosis and Therapy
MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.Schematic diagram of microneedle for cancer diagnosis and treatment. ABSTRACT As the global incidence of cancer continues to rise, the need for innovative and precisive alternatives to conventional diagnostic and therapeutic methods has become increasingly urgent.
Chunli Yang +9 more
wiley +1 more source
Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka +5 more
wiley +2 more sources
Opioid receptors in cardiovascular function
British Journal of Pharmacology, Volume 182, Issue 16, Page 3710-3725, August 2025.Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari +4 more
wiley +1 more source
Shifted Balance Between Ventral Striatal Prodynorphin and Proenkephalin Biases Development of Cocaine Place Avoidance. [PDF]
Addict BiolWe examined the optimum parameters for producing conditioned place avoidance (CPA) to the acutely aversive effects of cocaine treatment. We discovered that individual differences, rather than cocaine dose, apparatus type, stimulus modality or conditioning time, were important for expression of cocaine CPA.
Nicot A +4 more
europepmc +2 more sources
European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone +28 more
wiley +1 more source
The prenatal developmental profile of expression of opioid peptides and receptors in the mouse brain [PDF]
, 1991 R.A. Rius +4 more
openalex +1 more source
Mammalian Tolerance to Amino Acid Heterochirality
ChemBioChem, Volume 26, Issue 13, July 11, 2025.Organisms preferentially use l‐amino acids (l‐AAs). However, de novo synthesized l‐AAs are in part converted to d‐AAs. The ribosome has a robust system to use l‐AAs for protein synthesis, whereas non‐ribosomal synthesis can also use d‐AAs. Furthermore, some AA residues can be post‐translationally isomerized through enzymatic or spontaneous processes ...
Sakiko Taniguchi +4 more
wiley +1 more source