Journal of Neuroendocrinology, Volume 37, Issue 10, October 2025.Abstract We aimed to assess the symptoms and impact on overall survival (OS) from bone metastases (BM) diagnosed on Gallium‐68‐labelled DOTA tyrosine octreotide positron emission tomography with computed tomography (68Ga‐DOTATOC‐PET/CT) in patients with well‐differentiated small intestinal neuroendocrine tumours (Si‐NETs).
Maria Wedin +4 more
wiley +1 more source
Opioid peptides in cerebrospinal fluid-methods for analysis and their significance in the clinical perspective [PDF]
, 2004 Fred Nyberg
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The pharmacotherapeutic potential of neuropeptide Y for chronic pain
Journal of Internal Medicine, Volume 298, Issue 4, Page 280-296, October 2025.Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
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Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy
Journal of Sleep Research, Volume 34, Issue 5, October 2025.ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash +5 more
wiley +1 more source
Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys. [PDF]
Eur J Pharmacol, 2019 Cornelissen JC +6 more
europepmc +1 more source
Found in translation: orexin receptor antagonism for the treatment of opioid use disorder. [PDF]
Transl PsychiatryRaymond JS +3 more
europepmc +1 more source
Exploiting the angiotensin-converting enzyme pathway to augment endogenous opioid signaling. [PDF]
Commun BiolDobariya P +4 more
europepmc +1 more source
Constitutive activity of the Δ -opioid receptor expressed in C6 glioma cells: identification of non-peptide Δ -inverse agonists [PDF]
, 1999 Brett A. Neilan +3 more
openalex
The Neurotropic Activity of Novel Dermorphin Analogs Active at Systemic and Noninvasive Administration. [PDF]
Int J Mol SciDeigin V +7 more
europepmc +1 more source