Strategies to deliver peptide drugs to the brain [PDF]
Lalatsa, Katerina+2 more
core +1 more source
The glucagon‐like peptide‐1 (GLP‐1) receptor is regulated by distinct agonist‐induced and constitutive internalization pathways. Upon agonist stimulation, GLP‐1 receptor activates Gs and Gi/o, then recruits G protein–coupled receptor kinase 2/3/5/6 to phosphorylate the intracellular loops and C‐tail of the receptor.
Ee Von Moo+4 more
wiley +1 more source
Opioid Peptide Gene Expression in the Primary Hereditary Cardiomyopathy of the Syrian Hamster [PDF]
Carlo Ventura, Gianfranco Pintus
openalex +1 more source
Conformational Plasticity Enhances the Brain Penetration of a Metabolically Stable, Dual-Functional Opioid-Peptide CycloAnt. [PDF]
Li Y+9 more
europepmc +1 more source
Design, Synthesis and Pharmacological Evaluation of Novel Endomorphin Analogues with Multiple Structural Modifications [PDF]
Mallareddy Jayapal Reddy
core
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader+2 more
wiley +1 more source
Morphinomimetic activities of novel endogenous opioid peptides
Yujiro Hayashi+7 more
openalex +1 more source
Neuropharmacology: Effects on Rat Brain K1- and K2-Opioid Receptors after Chronic Treatment with Non-peptide K-Agonists [PDF]
Mona M. McConnaughey+2 more
openalex +1 more source
Delta opioid peptide [D-ala2, D-leu5]-Enkephalin's ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells. [PDF]
Deng Z+7 more
europepmc +1 more source