Results 231 to 240 of about 1,112,203 (348)

The 730 nm Picosecond Titanium Sapphire Laser for Treatment of Kratom‐Induced Hyperpigmentation

open access: yesLasers in Surgery and Medicine, Volume 57, Issue 5, Page 373-382, July 2025.
ABSTRACT Objectives This case series reports the use of the 730‐nm picosecond titanium‐sapphire laser in the treatment of kratom‐induced hyperpigmentation, a dermatological side effect associated with the use of Mitragyna speciosa, which remains poorly understood. Methods A series of patients with kratom‐induced hyperpigmentation were treated using the
Alanoud A. Alhadyani   +2 more
wiley   +1 more source

Obesity Biomarkers: Exploring Factors, Ramification, Machine Learning, and AI‐Unveiling Insights in Health Research

open access: yesMedComm, Volume 6, Issue 7, July 2025.
The graphical abstract emphasizes the complex nature of obesity, focusing on the interaction of behavioral, sociodemographic, genetic, and biomarker factors. It illustrates how lifestyle habits, demographics, and genetic predispositions influence obesity risk.
Ankita Awari   +8 more
wiley   +1 more source

Ten‐Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy

open access: yesMedComm, Volume 6, Issue 7, July 2025.
TET family proteins play a critical role in DNA demethylation, and their mutations and dysregulation contribute to the onset of multiple diseases. With a deeper understanding of the molecular mechanisms of TET involvement in disease, drug therapy targeting TET proteins shows great potential, which provides insights into new therapeutic strategies ...
Junzhi Liang   +12 more
wiley   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

open access: yesSmall, Volume 21, Issue 26, July 3, 2025.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun   +12 more
wiley   +1 more source

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors. [PDF]

open access: yesJ Enzyme Inhib Med Chem, 2017
Mollica A   +20 more
europepmc   +1 more source

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