Results 91 to 100 of about 448,610 (243)
Bioactive Peptides: A Review [PDF]
International Journal Bioautomation, 2011 Bioactive peptides have been defined as specific protein fragments that have a positive impact on body functions and conditions and may ultimately influence health [79].
Shrikant Sharma +2 more
doaj
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Opioid peptides in the female reproductive system: physiological implications [PDF]
, 1995 All endogenous opioid peptides derive from three precursor molecules i.e. proopiomelanocortin, proenkephalin and prodynorphin. The endogenous opioid peptides exert their biological effects through opioid receptors. Each endogenous opioid peptide exhibits
Makrigiannakis, Antonis; University of Crete +3 more
core +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
Peripheral targets for neuropathic pain
British Journal of Pharmacology, EarlyView.Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour +3 more
wiley +1 more source
Poultry Science: The effects of the administration of the opioid agonist, morphine, on plasma and tissue concentrations of Met-enkephalin were determined in 14 wk old female chickens.
Colin G. Scanes +1 more
doaj +1 more source
, 2014 Despite of the current availability of new synthetic drugs, morphine and the other alkaloids found in the opium poppy plant still represent the drugs of choice for the relief of serious pain caused by cancer or other maladies. However, long-term usage is
SPAMPINATO, SANTI MARIO +4 more
core
Regulation of the Estrous Cycle by Neutrophils via Opioid Peptides
, 2011 We found previously that neutrophil-depleted mice exhibited significant blockading of both the regular estrous cycle and cyclic changes of steroid hormone levels. In this study, we aimed at elucidation of the underlying mechanism.
Kisaburo Nagata +3 more
core +1 more source
British Journal of Pharmacology, EarlyView.Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang +5 more
wiley +1 more source
Neurobiology of Stress, 2018 Opioid peptides and their receptors re-organize within hippocampal neurons of female, but not male, rats following chronic immobilization stress (CIS) in a manner that promotes drug-related learning.
Matthew Randesi +8 more
doaj +1 more source