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Opioid and Anti-Opioid Peptides
Fundamental and Clinical Pharmacology, 1995Summary— The numerous endogenous opioid peptides (β‐endorphin, enkephalins, dynorphins…) and the exogenous opioids (such as morphine) exert their effects through the activation of receptors belonging to four main types: μ, Δ, k and ε. Opioidergic neurones and opioid receptors are largely distributed centrally and peripherally. It is thus not surprising
F Cesselin
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Non-Opioid Actions of Opioid Peptides
Life Sciences, 2004Beside the well known actions of opioid peptides on mu-, delta- and kappa-opioid receptors, increasing amount of pharmacological and biochemical evidence has recently been published about non-opioid actions of various opioid peptides. These effects are not abolished by naloxone treatments.
Sándor Benyhe, Maria Wollemann
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Expression of Opioid Peptides in Tumors
New England Journal of Medicine, 1987We looked for opioid peptides and their precursors in 108 tumors of both neuroendocrine and nonneuroendocrine origin, using a monoclonal "pan-opioid" antibody, 3-E7, which recognizes the tetrapeptide Tyr-Gly-Gly-Phe (the sequence responsible for pharmacologic activity in all known opioid peptides), in conjunction with polyclonal antibodies directed ...
Jack Barchas +2 more
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Opioid Peptides Encrypted in Intact Milk Protein Sequences [PDF]
British Journal of Nutrition, 2000 Opioid agonistic and antagonistic peptides which are inactive within the sequence of the precursor milk proteins can be released and thus activated by enzymatic proteolysis, for example during gastrointestinal digestion or during food processing ...
Richard J., Hans Meisel
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Annual Review of Pharmacology and Toxicology, 1979
Opioid peptides are endogenous or synthetic peptides, with a spectrum of pharmacological activity similar to that of morphine and other narcotic agonist drugs. The designation opioid peptide can be made if (a) it produces morphine-like, naloxone reversible effects in several in vitro bioassay sys tems such as the guinea pig ileum (1), the cat ...
A, Beaumont, J, Hughes
openaire +2 more sources
Opioid peptides are endogenous or synthetic peptides, with a spectrum of pharmacological activity similar to that of morphine and other narcotic agonist drugs. The designation opioid peptide can be made if (a) it produces morphine-like, naloxone reversible effects in several in vitro bioassay sys tems such as the guinea pig ileum (1), the cat ...
A, Beaumont, J, Hughes
openaire +2 more sources
Cancer and Metastasis Reviews, 2004
Opioid and somatostatin systems are two main inhibitory systems in mammals implicated in a variety of processes from hormone secretion to the modulation of cell proliferation. Opioids and opioid receptors were found in a great diversity of primary human tumors and in various cancer cell lines.
Jakub, Fichna, Anna, Janecka
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Opioid and somatostatin systems are two main inhibitory systems in mammals implicated in a variety of processes from hormone secretion to the modulation of cell proliferation. Opioids and opioid receptors were found in a great diversity of primary human tumors and in various cancer cell lines.
Jakub, Fichna, Anna, Janecka
openaire +2 more sources