Results 231 to 240 of about 1,054,479 (288)

Biosynthesis of Opioid Peptides

1990
The endogenous opioid peptides all contain the enkephalin sequence Tyr-Gly-Gly-Phe-Met and Tyr-Gly-Gly-Phe-Leu at their aminoterminus. Three distinct families of these peptides (endorphins, enkephalins and dynorphins) are present in different neuronal pathways within the central nervous system. Molecular genetics have shown that these three families of
openaire   +3 more sources

Chapter 18 Nicotine and opioid peptides

1989
Publisher Summary This chapter discusses the relationship between nicotinic cholinergic receptors and opioid peptides. Nicotine appears to exert its stimulatory effect most likely at the level of the hypothalamus by causing a release of corticotropin releasing factor.
Gabriele Horn, V. Höllt
openaire   +3 more sources

Analysis of opioid peptides by on‐line SPE‐CE‐ESI‐MS

Electrophoresis, 2007
In this study, SPE‐CE‐ESI‐MS is explored for the preconcentration and separation of dilute solutions of six opioid peptides. First, a CE‐ESI‐MS methodology was developed and validated.
E. Hernández, F. Benavente, V. Sanz-Nebot, J. Barbosa   +3 more
semanticscholar   +1 more source

Endomorphins and related opioid peptides

2002
Opioid peptides and their G-protein-coupled receptors (delta, kappa, mu) are located in the central nervous system and peripheral tissues. The opioid system has been studied to determine the intrinsic mechanism of modulation of pain and to develop uniquely effective pain-control substances with minimal abuse potential and side effects.
Sharon D. Bryant, Yoshio Okada, Lawrence H. Lazarus, Yuko Tsuda   +3 more
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OPIOID PEPTIDES

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semanticscholar   +1 more source

Pain control by CXCR2 ligands through Ca2+ ‐regulated release of opioid peptides from polymorphonuclear cells

The FASEB Journal, 2006
Leukocytes counteract inflammatory pain by releasing opioid peptides, which bind to opioid receptors on peripheral sensory neurons. In the early phase of inflammation, polymorphonuclear cells (PMN) are the major source of opioids.
H. Rittner, D. Labuz, Michael Schaefer, S. Mousa, S. Schulz, M. Schäfer, C. Stein, A. Brack   +7 more
semanticscholar   +1 more source

Conformation-activity relationships of opioid peptides with selective activities at opioid receptors.

Biopolymers, 1999
The discovery of endogenous opioid peptides 25 years ago opened up a new chapter in efforts to understand the origins and control of pain, its relationships to other biological functions, including inflammatory and other immune responses, and the ...
Victor J. Hruby, R. S. Agnes
semanticscholar   +1 more source

Delta opioid peptides derived from plant proteins.

Current pharmaceutical design, 2003
Opioid peptides showing selectivity for delta receptor have been isolated from enzymatic digests of plant proteins. Five peptides were derived from wheat gluten, and named gluten exorphins A5, A4, B5, B4 and C. Two opioid peptides were also released from
M. Yoshikawa, M. Takahashi, S. Yang
semanticscholar   +1 more source

Palatal myoclonus and opioid peptides

Acta Neurologica Scandinavica, 2009
We report a patient who presented palatal myoclonus (PM) after anoxic brain damage that was completely abolished by the administration of opioid agonists. This suggests the involvement of peptide systems in the development of PM.
P. Martínez‐Lage Alvarez, Maria-Rosario Luquin, J. M. Martínez‐Lage, Eduardo Martínez-Vila   +3 more
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Distribution of opioid peptides in the preoptic region: Immunohistochemical evidence for a steroid‐sensitive enkephalin sexual dimorphism

The Journal of comparative neurology, 1988
The distribution of cells and fibers that contain opioid peptides within the preoptic region of the rat was examined immunohistochemically. Cells and/or fibers that contain peptides derived from each of the three major opioid peptide families were ...
R. Simerly, L. D. McCall, S. Watson
semanticscholar   +1 more source