Results 231 to 240 of about 1,102,643 (357)
The Role of Inflammation in Migraine Headaches: A Review
Inflammation plays a crucial role in the onset and intensity of both migraine headache symptoms and attacks. Pro‐inflammatory neurotransmitters and mediators released from neural cells and tissues that contributes to increase in nitric oxide, increase in glutamate, alterations in serotonin and dopamine levels and pain perception are involved in ...
Caryn T. Morgan, Sanah M. Nkadimeng
wiley +1 more source
We examined the optimum parameters for producing conditioned place avoidance (CPA) to the acutely aversive effects of cocaine treatment. We discovered that individual differences, rather than cocaine dose, apparatus type, stimulus modality or conditioning time, were important for expression of cocaine CPA.
Amélia Nicot+4 more
wiley +1 more source
Tonic inhibitory control exerted by opioid peptides in the paraventricular nuclei of the hypothalamus on regional hemodynamic activity in rats [PDF]
Andrée Lessard, Hélène Bachelard
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ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga+7 more
wiley +1 more source
Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings. [PDF]
Willemse T+13 more
europepmc +1 more source
Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain [PDF]
Victor J. Hruby+7 more
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Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi+6 more
wiley +1 more source
Absence of urinary opioid peptides in children with autism
H. Cass+6 more
semanticscholar +1 more source
Comparative drugability evaluation of MOR opioid peptides in functional brain research [PDF]
Adriaens, Antita+6 more
core
Microscopy and spectroscopy approaches to study GPCR structure and function
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl+2 more
wiley +1 more source