Results 271 to 280 of about 45,822 (323)
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Non-opioid actions of opioid peptides
Life Sciences, 2004Beside the well known actions of opioid peptides on mu-, delta- and kappa-opioid receptors, increasing amount of pharmacological and biochemical evidence has recently been published about non-opioid actions of various opioid peptides. These effects are not abolished by naloxone treatments.
Maria Wollemann, Sándor Benyhe
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Biosynthesis and distribution of opioid peptides [PDF]
Journal of Endocrinological Investigation, 1983 Group III opioid peptides are derived from proenkephalin B. The processing of this precursor peptide is still only partly understood and we still do not know how many final products come from proenkephalin B and whether Leu-enkephalin is produced from Group III peptides.
I. Tanaka +10 more
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Biosynthesis of Opioid Peptides
1990The endogenous opioid peptides all contain the enkephalin sequence Tyr-Gly-Gly-Phe-Met and Tyr-Gly-Gly-Phe-Leu at their aminoterminus. Three distinct families of these peptides (endorphins, enkephalins and dynorphins) are present in different neuronal pathways within the central nervous system. Molecular genetics have shown that these three families of
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Chapter 18 Nicotine and opioid peptides
1989Publisher Summary This chapter discusses the relationship between nicotinic cholinergic receptors and opioid peptides. Nicotine appears to exert its stimulatory effect most likely at the level of the hypothalamus by causing a release of corticotropin releasing factor.
Gabriele Horn, V. Höllt
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Endomorphins and related opioid peptides
2002Opioid peptides and their G-protein-coupled receptors (delta, kappa, mu) are located in the central nervous system and peripheral tissues. The opioid system has been studied to determine the intrinsic mechanism of modulation of pain and to develop uniquely effective pain-control substances with minimal abuse potential and side effects.
Sharon D. Bryant +3 more
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Expression of Opioid Peptides in Tumors
New England Journal of Medicine, 1987We looked for opioid peptides and their precursors in 108 tumors of both neuroendocrine and nonneuroendocrine origin, using a monoclonal "pan-opioid" antibody, 3-E7, which recognizes the tetrapeptide Tyr-Gly-Gly-Phe (the sequence responsible for pharmacologic activity in all known opioid peptides), in conjunction with polyclonal antibodies directed ...
Klaus G. Bensch +5 more
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Opioid Peptides and Vasopressin
1986During the past several years, several of the neuroscience disciplines have increasingly assumed both the character and methodologies of classical molecular biology. In large part, this inundation reflects our need to investigate and understand the “pretranslational” events governing the regulation of peptide hormone and receptor expression throughout ...
Henry Khachaturian +5 more
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Palatal myoclonus and opioid peptides
Acta Neurologica Scandinavica, 2009We report a patient who presented palatal myoclonus (PM) after anoxic brain damage that was completely abolished by the administration of opioid agonists. This suggests the involvement of peptide systems in the development of PM.
P. Martínez‐Lage Alvarez +3 more
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Opioid peptides and their receptors [PDF]
, 1986 The endogenous opioid peptides belong to three groups: the endorphins, the enkephalins and the dynorphins. These three groups are clearly distinct chemical families derived from three different precursor peptides: pro-opiomelanocortin. proenkephalin and prodynorphin.
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