Results 271 to 280 of about 1,122,610 (333)

Biosynthesis of Opioid Peptides

1990
The endogenous opioid peptides all contain the enkephalin sequence Tyr-Gly-Gly-Phe-Met and Tyr-Gly-Gly-Phe-Leu at their aminoterminus. Three distinct families of these peptides (endorphins, enkephalins and dynorphins) are present in different neuronal pathways within the central nervous system. Molecular genetics have shown that these three families of
openaire   +2 more sources

The Opioid Peptides

1988
The discovery of endogenous opioids has begun an intricate saga involving multiple ligands and multiple receptors that form an extensive neuronal network in both the central and peripheral nervous systems. This intricacy is reflected in the complex pharmacology and diverse physiological effects of opioids in mammals.
Christopher J. Evans, Donna L. Hammond, Robert C. A. Frederickson   +2 more
openaire   +1 more source

Expression of Opioid Peptides in Tumors

New England Journal of Medicine, 1987
We looked for opioid peptides and their precursors in 108 tumors of both neuroendocrine and nonneuroendocrine origin, using a monoclonal "pan-opioid" antibody, 3-E7, which recognizes the tetrapeptide Tyr-Gly-Gly-Phe (the sequence responsible for pharmacologic activity in all known opioid peptides), in conjunction with polyclonal antibodies directed ...
D G, Bostwick, W E, Null, D, Holmes, E, Weber, J D, Barchas, K G, Bensch   +5 more
openaire   +2 more sources

Biosynthesis and distribution of opioid peptides

Journal of Endocrinological Investigation, 1983
Group III opioid peptides are derived from proenkephalin B. The processing of this precursor peptide is still only partly understood and we still do not know how many final products come from proenkephalin B and whether Leu-enkephalin is produced from Group III peptides.
H, Imura, Y, Nakai, K, Nakao, S, Oki, I, Tanaka, H, Jingami, T, Yoshimasa, T, Tsukada, Y, Ikeda, M, Suda, M, Sakamoto   +10 more
openaire   +2 more sources

Opioid peptides in adrenal gland

Life Sciences, 1980
Abstract Enkephalin-like immunoreactive peptides have been observed in adrenal glands of all species studied with the highest contents found in dogs and cows, and the lowest in rats. These peptides are located both in gland cells and in afferent nerve terminals. Bovine adrenal glands contain opioid peptides in many molecular forms.
H Y, Yang, T, Hexum, E, Costa
openaire   +2 more sources

Palatal myoclonus and opioid peptides

Acta Neurologica Scandinavica, 2009
We report a patient who presented palatal myoclonus (PM) after anoxic brain damage that was completely abolished by the administration of opioid agonists. This suggests the involvement of peptide systems in the development of PM.
E, Martínez-Vila, P, Martínez-Lage Alvarez, M R, Luquin, J M, Martínez-Lage   +3 more
openaire   +2 more sources

OPIOID PEPTIDES

British Medical Bulletin, 1977
J, Hughes, H W, Kosterlitz
openaire   +2 more sources

Opioid Peptides and Protein Phosphorylation

1979
The identification and isolation of naturally occur ring neuropeptides with morDhine-like activity was first reported by Hughes (1975) and co-workers (HUGHES, et al, 1975). These compounds were named methionine-enkephalin and leucine-enkephalin and have the amino-acid sequences of Tyr-Gly-Gly-Phe-Met and Tyr-Gly-Gly-Phe-Leu, respectively. Subsequently,
L G, Davis, Y H, Ehrlich
openaire   +2 more sources

Melanins From Opioid Peptides

Pigment Cell Research, 1996
Opioid peptides and other Tyr‐NH2‐terminal peptides are substrates in vitro for mushroom and sepia tyrosinase, giving rise to synthetic melanins retaining the peptide moiety (opiomelanins). The melanopeptides are characterized by a total solubility in hydrophylic solvents at neutral and basic pH. Opioid peptides (enkephalins, endorphins, and esorphins),
openaire   +2 more sources

Opioid Peptides and Aging

Annals of the New York Academy of Sciences, 1990
J E, Morley, J F, Flood, A J, Silver
openaire   +2 more sources