Results 171 to 180 of about 2,542,870 (405)
Close collaboration between an Australian drug checking service and an affiliated university laboratory identifies and characterises the novel synthetic opioid N‐pyrrolidino isotonitazene in an expected oxycodone sample presented by a member of the public.
Blake Curtis+3 more
wiley +1 more source
Nitrous Oxide Acts Directly at the Mu Opioid Receptor [PDF]
Mark A. Gillman, F J Lichtigfeld
openalex +1 more source
ABSTRACT Objective Avoidant restrictive food intake disorder (ARFID) is a relatively new diagnostic entity, and no medication has been approved. Recent data suggest that mirtazapine, a tetracyclic antidepressant, could improve outcomes in ARFID. We conducted a retrospective chart review to examine the effects of mirtazapine on ARFID treatment in youth.
Aman Chishti+6 more
wiley +1 more source
Behavioral and pharmacological characterization of a mouse model of palatable diet alternation [PDF]
Obesity and eating disorders represent a severe problem in Western societies. Both the increased availability of highly palatable foods and dieting are major risk factors contributing to the epidemic disorders of feeding. The purpose of this study was to
Schlain, Gabrielle Star
core
In‐hospital and 1 year incremental prognostic value of drug abuse detection in acute heart failure
Abstract Aims The study aims to assess the in‐hospital and 1 year incremental prognostic value of recent drug abuse use, detected by a systematic urinary screening, in a consecutive cohort of patients hospitalized for acute heart failure (AHF). Methods All patients admitted for AHF with a drug abuse screening using a urinary assay were included in this
Charles Fauvel+110 more
wiley +1 more source
ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L+10 more
core
(A) Univariable receiver operating characteristic (ROC) curves for all biomarkers. (B) Kaplan–Meier curves for best cut‐point of mid‐regional pro‐adrenomedullin (MR‐proADM) for survival (n = 442). AUC, area under the curve; CI, confidence interval; HR, hazard ratio; hsTnT, high‐sensitivity troponin T; MR‐proANP, mid‐regional pro‐atrial natriuretic ...
Markus S. Anker+18 more
wiley +1 more source
Current and novel biomarkers in cardiogenic shock
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko+5 more
wiley +1 more source