Results 251 to 260 of about 87,734 (315)

Peripheral Analgesic Effect of a Novel Curcuminoid Derivative: Possible Involvement of Peripheral Opioid Receptor and ATP-Sensitive Potassium Ion Channel. [PDF]

Pharmaceutics
Lee MT, Ho YC, Tham CL, Akira A, Lajis N, Israf DA, Sulaiman MR.   +6 more
europepmc   +1 more source

Extracellular processing of proopiomelanocortin generates short beta endorphin that regulates rat keratinocytes via the delta opioid receptor. [PDF]

Sci Rep
Yamamoto H, Sawaguchi Y, Koida A, Yamada T.   +3 more
europepmc   +1 more source

Delta Opioid Receptors and Cardioprotection

, 2017
The opioid receptor family, with associated endogenous ligands, has numerous roles throughout the body. Moreover, the delta opioid receptor (DORs) has various integrated roles within the physiological systems, including the cardiovascular system.
Hoe, Louise See, Patel, Hemal H, Peart, Jason N   +2 more
openaire   +6 more sources

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Opioid Receptors

Annual Review of Biochemistry, 2004
▪ Abstract  Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones. Opioid receptors are particularly intriguing members of this receptor family.
Waldhoer, Maria, Bartlett, Selena E., Whistler, Jennifer L.   +2 more
openaire   +4 more sources

Opioid Receptors and their Ligands

Current Topics in Medicinal Chemistry, 2004
This review gives a historical perspective, summarizing approximately 25 years of research on opioids. The "typical" opioid peptides produced in the brain, "atypical" opioids encrypted in milk protein or hemoglobin sequences, and extremely potent and selective opioids of amphibian origin are described.
Anna, Janecka, Jakub, Fichna, Tomasz, Janecki   +2 more
openaire   +2 more sources

Opioid receptor polymorphismsand opioid abuse

Pharmacogenomics, 2002
The sequencing of the human genome is only the first step. The next step is to determine the function of these genes and in particular, how alterations in specific genes lead to major human disorders. Many laboratories are now focusing on identifying and characterizing single nucleotide polymorphisms (SNPs), to determine which correlate in frequency ...
Nancy M, Lee, Andrew P, Smith
openaire   +2 more sources

Opioids, opioid receptors, and the immune response

Drug and Alcohol Dependence, 2001
It is now clear that opioid receptors participate in the function of the cells of the immune system, and evidence suggests that opioids modulate both innate and acquired immune responses. We review literature here which establishes that mu-, kappa-, and delta-opioid compounds alter resistance to a variety of infectious agents, including the Human ...
L, McCarthy, M, Wetzel, J K, Sliker, T K, Eisenstein, T J, Rogers   +4 more
openaire   +2 more sources

Opioids and Opioid Receptors in Peripheral Tissues

Scandinavian Journal of Gastroenterology, 1987
Opioid peptides belonging to the enkephalin, beta-endorphin or dynorphin family, acting on specific opiate receptors may be found in peripheral tissues. Enkephalins have a widespread peripheral distribution, while beta-endorphin and dynorphin may be found locally in the enteric nervous system.
T, Hedner, J, Cassuto
openaire   +2 more sources

Steroids and opioid receptors

The Journal of Steroid Biochemistry and Molecular Biology, 1994
The genomic mode of action is believed to represent the predominant effect of a steroid hormone. Recently, however, rapidly manifesting, non-genomic effects have also been observed. These are mediated mostly by allosteric interaction of a steroid with heterologous target structures such as membrane receptors, a prototype example being the GABAA.
S, Schwarz, P, Pohl
openaire   +2 more sources