Results 241 to 250 of about 87,734 (315)

Emotion processing in schizophrenia and its relation to μ-opioid receptor availability. [PDF]

Neuroimage Clin
Shatalina E, Ashok AH, Wall MB, Myers J, Marques TR, Rabiner EA, Howes OD.   +6 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Casomorphine-10 (CM-10) Peptide Orchestrates Circadian and Neurodevelopmental Gene Clusters via δ-Opioid Receptor Signaling: Insights from Transcriptome Analysis with δ-Opioid Receptor-Expressing HEK293 Cells. [PDF]

Life (Basel)
Fukunaga M, Watanabe S, Orihara K, Yamamoto N.   +3 more
europepmc   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola, Aislinn O'Kane, Michael Heathman, Hannah Marotta, Hayley Trussel, Bobbie Ray, Shelley Dowden, Andrea R. Masters, David M. Haas, Sara K. Quinney   +9 more
wiley   +1 more source

μ-Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks. [PDF]

Ann Neurol
Kim DJ, Lim M, Nascimento TD, Porreca F, Koeppe RA, Hadjikhani N, DaSilva AF.   +6 more
europepmc   +1 more source

Respiratory Events and Procedure Interruptions During Pediatric Bronchoscopy and Suspension Laryngoscopy: A Secondary Analysis Comparing Dexmedetomidine and Remifentanil‐Based Anesthesia

Pediatric Anesthesia, EarlyView.
Clyde T. Matava, Brenda Nkonge, Martina Bordini, Julia M. Olsen, Jennifer M. Siu, Jason Macartney, Nikolaus E. Wolter, Evan J. Propst   +7 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Structural Determinants of Buprenorphine Partial Agonism at the μ-Opioid Receptor. [PDF]

J Chem Inf Model
Gomes AAS, Giraldo J.
europepmc   +1 more source

Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor. [PDF]

Nat Commun
Suno-Ikeda C, Nishikawa R, Suzuki R, Yokoi S, Iwata S, Takai T, Ogura T, Hirose M, Tokuda A, Katamoto R, Inoue A, Asai E, Kise R, Sugita Y, Kato T, Nagase H, Mitsutake A, Saitoh T, Katayama K, Inoue A, Kandori H, Kobayashi T, Suno R.   +22 more
europepmc   +1 more source

Aberrant type 2 dopamine and mu-opioid receptor availability in autism spectrum disorder. [PDF]

Eur J Nucl Med Mol Imaging
Noppari T, Tuisku J, Lukkarinen L, Tani P, Lindberg N, Saure E, Lauerma H, Tiihonen J, Hirvonen J, Helin S, Rajander J, Salmi J, Nummenmaa L.   +12 more
europepmc   +1 more source