Results 221 to 230 of about 1,391,378 (297)

Structure-based design of an opioid receptor modulator for enhanced morphine analgesia. [PDF]

Sci Adv
Wang Y, Luo P, Xu H, Zhan L, Sakamoto K, Li M, Wang J, Huang XP, Zhou J, Liu T, Suo Y, Fan W, He X, Xu Y, Cai Y, Wang C, Zhao Y, Dai A, Lai Y, Yuan Q, Hu W, Wu K, Yang D, Cheng X, Lu X, Krumm B, Kenakin T, Zhang J, Roth BL, Gao Z, Xu HE, Zhuang Y.   +31 more
europepmc   +1 more source

Malnutrition in cancer surgery: A retrospective study on screening practices and outcomes

Nutrition in Clinical Practice, EarlyView.
Abstract Background Preoperative nutrition risk screening and referral for optimization are recommended for patients undergoing cancer surgery; however, despite high‐risk individuals being identified, referral remains variable. This study aimed to determine the prevalence of preoperative undernutrition risk and body mass index (BMI)‐defined ...
Noha Elsherbini, Bhagya Tahasildar, Tarsan Sangarapillai, Vanessa D. Gueorguieva, Sepehr Mehrpouyan, Tawfik Elsherbini, Matei Cotoros, Dong Hyun Kim, Francesco Carli, Chelsia Gillis   +9 more
wiley   +1 more source

κ-opioid receptor: from analgesic target to neuroimmune hub. [PDF]

Front Pharmacol
Tan Q, Zheng M, Xing H.
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

A kappa opioid receptor agonist, difelikefalin, improves acute kidney injury in experimental sepsis models. [PDF]

PLoS One
Sawanobori Y, Nakano D, Kitamura H, Kitada K, Asaga T, Suzuki N, Yamamoto M, Ogino Y, Shirakami G, Nishiyama A.   +9 more
europepmc   +1 more source

Nonpharmacologic Therapy for Pediatric Posttonsillectomy Pain: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To understand efficacies of nonpharmacologic therapy for pediatric posttonsillectomy pain. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus. Review Methods Studies on nonpharmacologic interventions for pediatric posttonsillectomy pain were included in this systematic review.
Justina T. Sargios, David Kayekjian, Shaun A. Nguyen, Pete Peters, Clarice S. Clemmens, William W. Carroll   +5 more
wiley   +1 more source

Functional significance of opioid receptor homomers and heteromers. [PDF]

Nat Commun
Ferré S, Ciruela F, Pardo L.
europepmc   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 3—One Center's Evolving Regional Anesthesia Experience and Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery is the dominant model of surgical care in the U.S. and has impacted the practice of regional anesthesia (RA). Pediatric RA's use has expanded as a supplement to general anesthesia with the introduction of ultrasound.
David E. Liston, Elizabeth E. Hansen, Jennifer L. Chiem, Sean H. Flack, Daniel K. W. Low, Lynn D. Martin   +5 more
wiley   +1 more source

Effects of Esketamine on Emergence Delirium in Children Undergoing Sevoflurane Anesthesia: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium is a frequent and distressing postoperative complication in children, particularly following sevoflurane‐based anesthesia. Despite its clinical importance, the optimal preventive strategy remains under investigation.
Munder Lateiresh, Abdelaziz Louat, Mukhtar Alwefati, Alhasan Altayf, Matthieu Legrand, Phillip D. Cohen, Eman Abdulwahed, Sapna R. Kudchadkar, Muhammed Elhadi   +8 more
wiley   +1 more source

A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Robin sequence (RS) is characterized by upper airway obstruction leading to life‐threatening desaturations in neonates. Procedural sedation in this population presents unique challenges due to anatomical airway anomalies, young patient age, and associated comorbidities.
Nicolas Leister, Sarah Achterrath, Uwe Trieschmann, Teresa Kruse, Bert Braumann, Volker C. Schick   +5 more
wiley   +1 more source