Results 221 to 230 of about 87,734 (315)

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Neuronal Colocalization of μ-Opioid Receptor, κ-Opioid Receptor, and Oxytocin Receptor mRNA in the Central Nucleus of the Amygdala in Male and Female Mice. [PDF]

eNeuro
Nisbett KE, Koob GF.
europepmc   +1 more source

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash de Barros Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source

Trifluoromethylthio and Trifluoromethyl Functionalization of Endomorphin-1 Enhances its Hydrophobicity and Plasma Stability while Preserving its Affinity for the μ-Opioid Receptor. [PDF]

J Org Chem
Gregorc J, De Neve J, Guitot K, Holleran BJ, Lensen N, Gendron L, Brigaud T, Iskra J, Ballet S, Chaume G.   +9 more
europepmc   +1 more source

Persistent Mu-Opioid Receptor Dysregulation in a Pain-Facilitatory Brain Region Reinstates Hyperalgesia After Resolution of Opioid-Induced Hyperalgesia. [PDF]

Pharmaceuticals (Basel)
Sousa M, Costa AR, Tavares I, Martins I.
europepmc   +1 more source

Median Effective Volume of 0.2% Ropivacaine for Ultrasound‐Guided Axillary Brachial Plexus Block in Children Aged 6–10 Years: A Prospective Dose‐Finding Study Using Up‐and‐Down Sequential Allocation

Pediatric Discovery, EarlyView.
Purpose: This study aimed to determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound‐guided axillary brachial plexus block (ABPB) in children aged 6–10 years, using the Dixon up‐and‐down method. The EV50 was 0.350 mL/kg (95% CI: 0.197–0.362 mL/kg), calculated by isotonic regression and bootstrapping.
Tauseef Ahmad, Fei Yang, Yao Xu, Ying Yang, Huanjie Yun, Fei Xu, Yulin Xue, Yu Zhou, Zongke Shi, Yuan Shi, Shangyingying Li, Shengfen Tu   +11 more
wiley   +1 more source

Structural snapshots capture nucleotide release at the μ-opioid receptor. [PDF]

Nature
Khan S, Tyson AS, Ranjbar M, Zhang Z, Singh J, Han GW, Gati C.   +6 more
europepmc   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Mechanistic Insights into G Protein-Biased κ-Opioid Receptor Signaling Using Dual-Charged Naltrexamine Amides. [PDF]

J Med Chem
Doering NP, Puls K, Diceglie M, Meraner A, Hentsch A, Hongnak S, Wurzer A, Schmidhammer H, Spetea M, Nazare M, Wolber G.   +10 more
europepmc   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source