Results 341 to 350 of about 2,577,172 (407)

The Long Arc of Substance Use Policy Innovation in Medicaid: Looking Back, Looking Forward

The Milbank Quarterly, EarlyView.
Policy Points The role of Medicaid in financing, organizing, and delivering substance use disorder (SUD) treatment has grown tremendously over time owing to expansions of eligibility and a push toward more uniformity in benefits. Current innovations in SUD treatment focus on expanding the delivery system to create a comprehensive continuum of care ...
BRENDAN SALONER
wiley   +1 more source

Reversal of morphine-induced respiratory depression with the µ₁-opioid receptor antagonist naloxonazine engenders excitation and instability of breathing. [PDF]

Am J Physiol Lung Cell Mol Physiol
Getsy PM, May W, Henderson F, Coffee GA, Baby SM, Hsieh YH, Lewis SJ.   +6 more
europepmc   +1 more source

Anti-inflammatory and renoprotective effects of difelikefalin, a kappa opioid receptor agonist, in a rat model of renal ischemia-reperfusion-induced acute kidney injury. [PDF]

BMC Nephrol
Takeuchi H, Tatemichi S, Okuhara Y.
europepmc   +1 more source

Reversal of Diabetic Dry Eye by Topical Opioid Receptor Blockade Follows Dual Pathways. [PDF]

Invest Ophthalmol Vis Sci
Diaz D, Sassani JW, Zagon IS, McLaughlin PJ.   +3 more
europepmc   +1 more source

Kappa opioid receptor internalisation-induced p38 nuclear translocation suppresses glioma progression. [PDF]

Br J Anaesth
Li Y, Wang W, She H, Cui Z, Liu Z, Yang H, Zhang J, Zhou X, Bao D, Yao Y, Luo S, Cai R, Shi Y, Ping YF, Mao Q.   +14 more
europepmc   +1 more source

Correction: Delta opioid receptor agonists activate PI3K-mTORC1 signaling in parvalbumin-positive interneurons in mouse infralimbic prefrontal cortex to exert acute antidepressant-like effects. [PDF]

Mol Psychiatry
Yoshioka T, Yamada D, Hagiwara A, Kajino K, Iio K, Saitoh T, Nagase H, Saitoh A.   +7 more
europepmc   +1 more source

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Opioid Receptors

Annual Review of Biochemistry, 2004
▪ Abstract  Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones. Opioid receptors are particularly intriguing members of this receptor family.
Waldhoer, Maria, Bartlett, Selena E., Whistler, Jennifer L.   +2 more
openaire   +4 more sources

Opioid receptor polymorphismsand opioid abuse [PDF]

Pharmacogenomics, 2002
The sequencing of the human genome is only the first step. The next step is to determine the function of these genes and in particular, how alterations in specific genes lead to major human disorders. Many laboratories are now focusing on identifying and characterizing single nucleotide polymorphisms (SNPs), to determine which correlate in frequency ...
Andrew P. Smith, Nancy M. Lee
openaire   +2 more sources

Opioid Receptors and their Ligands

Current Topics in Medicinal Chemistry, 2004
This review gives a historical perspective, summarizing approximately 25 years of research on opioids. The "typical" opioid peptides produced in the brain, "atypical" opioids encrypted in milk protein or hemoglobin sequences, and extremely potent and selective opioids of amphibian origin are described.
Tomasz Janecki, Anna Janecka, Jakub Fichna   +2 more
openaire   +3 more sources