Results 161 to 170 of about 135,910 (355)

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger, Florian Brugger, Georg Kägi, Jens Carsten Möller, Nathalie Hollenstein, David H. Benninger, Michele Tinazzi, Julien F. Bally, Roman Gonzenbach, Daniel Ciampi de Andrade, Santiago Perez Lloret, Veit Mylius   +11 more
wiley   +1 more source

Oxycodone regulates incision-induced activation of neurotrophic factors and receptors in an acute post-surgery pain rat model

Journal of Pain Research, 2018
Baowen Liu, Yi Liu, Ningbo Li, Jin Zhang, Xianwei Zhang Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Background: Oxycodone, which is one of the most commonly used ...
Liu BW, Liu Y, Li NB, Zhang J, Zhang XW
doaj  

Transfection of NG108-15 cells with antisense opioid-binding cell adhesion molecule cDNA alters opioid receptor-G-protein interaction.

, 1993
Piyarat Govitrapong, Xiaofeng Zhang, Horace H. Loh, Noven Lee   +3 more
openalex   +1 more source

Opioid receptors.

Japanese Journal of Pharmacology, 1985
openaire   +2 more sources

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake

, 2020
Daniel W. Bloodgood, J. Andrew Hardaway, Christina M. Stanhope, Dipanwita Pati, Melanie M. Pina, Sofia Neira, Shivani Desai, Kristen M. Boyt, Richard D. Palmiter, Thomas L. Kash   +9 more
openalex   +2 more sources

Innovation in Rural Nonprofits: Which Organizational Capacities Matter Most?

Nonprofit Management and Leadership, EarlyView.
ABSTRACT This research note draws on theory and empirical research from the broader fields of management, organizational capacity, and innovation to examine how specific organizational capacities relate to innovation in a sample of 107 rural nonprofit organizations in a Southeastern U.S. state.
Kristina Jaskyte, Ashley Hunter, Lina Danusevičienė   +2 more
wiley   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source