Results 11 to 20 of about 2,447,948 (384)
Molecules, 2022 Opioid receptors are members of the group of G protein-couple receptors, which have been proven to be effective targets for treating severe pain. The interactions between the opioid receptors and corresponding ligands and the receptor’s activation by ...
Peng Xie +8 more
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Bidirectional Regulation of Opioid and Chemokine Function
Frontiers in Immunology, 2020 The opioid family of GPCRs consists of the classical opioid receptors, designated μ-, κ-, and δ-opioid receptors, and the orphanin-FQ receptor, and these proteins are expressed on both neuronal and hematopoietic cells.
Thomas J. Rogers
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Cocaine modulates the expression of opioid receptors and miR-let-7d in zebrafish embryos. [PDF]
PLoS ONE, 2012 Prenatal exposure to cocaine, in mammals, has been shown to interfere with the expression of opioid receptors, which can have repercussions in its activity.
Roger López-Bellido +3 more
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Frontiers in Molecular Neuroscience, 2022 Impaired chemoreflex responses are a central feature of opioid-induced respiratory depression, however, the mechanism through which mu opioid receptor agonists lead to diminished chemoreflexes is not fully understood.
Sebastian N. Maletz +5 more
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Prescription analgesic overuse in older adults: Can we mitigate this growing problem?
AGING MEDICINE, Volume 5, Issue 4, Page 294-296, December 2022., 2022 With older adults already on numerous prescription medications to manage their chronic conditions, the addition of pain medications could impose an even greater burden due to dependency issues. We need to understand the use of chronic pain medication, especially opioids, discuss current strategies and gaps, and offer potential solutions to mitigate ...
Sara Kakatkar +2 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 131-137, January 2023., 2023 The cornerstone of treatment for symptomatic gallbladder stones is laparoscopic cholecystectomy. Pain is the commonest cause of extended hospital stay. Disturbance of liver—diaphragm surface tension is the main cause of pain. Retained CO2 is a major concern post laparoscopic cholecystectomy.
Mohamed Lotfy Ali Abuelzein +3 more
wiley +1 more source
Interactions between $β$-endorphin and kisspeptin neurons of the ewe arcuate nucleus are modulated by photoperiod [PDF]
Journal of Neuroendocrinology, In press, 2023 Opioid peptides are well-known modulators of the central control of reproduction. Among them, dynorphin coexpressed in kisspeptin (KP) neurons of the arcuate nucleus (ARC) has been thoroughly studied for its autocrine effect on KP release through $\kappa$ opioid receptors.
arxiv +1 more source
American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023 Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter +14 more
wiley +1 more source
Frontiers in Pharmacology, 2020 Opioids are the most effective analgesics used in the clinical management of cancer pain or non-cancer pain. However, chronic opioids therapy can cause many side effects including respiratory depression, nausea, sedation, itch, constipation, analgesic ...
Li Zhang +4 more
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