Results 191 to 200 of about 130,157 (357)

[3H]U-69593; a highly selective ligand for the opioid κ receptor

, 1985

openalex   +1 more source

Differential effects of K⁺ channel blockers on antinociception induced by α₂‐adrenoceptor, GABA_B and κ‐opioid receptor agonists [PDF]

, 1993
Maria Ocaña, José M. Baeyens
openalex   +1 more source

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

The Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub, Shen Cheng, Mohamed S. Fayed, James Fisher, Jillian Brooks, Elizabeth Seaquist, Anjali Kumar, Amir Moheet, Lynn Eberly, Lisa D. Coles   +9 more
wiley   +1 more source

Endogenous opioid receptors and the feast or famine of maladaptive feeding. [PDF]

Nat Commun
Sutton Hickey AK, Matikainen-Ankney BA.
europepmc   +1 more source

The Downregulation of Opioid Receptors and Neuropathic Pain. [PDF]

Int J Mol Sci, 2023
Li L, Chen J, Li YQ.
europepmc   +1 more source

Differential ontogeny of multiple opioid receptors (μ, δ, and κ)

, 1985
J.W. Spain, B.L. Roth, C.J. Coscia
openalex   +2 more sources

Effects of preferential delta and kappa opioid receptor agonists on the intake of hypotonic saline [PDF]

, 1990
Blake A. Gosnell, Mark J. Majchrzak, Dean D. Krahn   +2 more
openalex   +1 more source

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M. T. Sherwin, Anne van Rongen, Daniëlla W. E. Roofthooft, Sinno H. P. Simons, Dick Tibboel, Robert B. Flint, John N. van den Anker, Catherijne A. J. Knibbe   +11 more
wiley   +1 more source

Peripheral Opioid Receptors in the Modulation of Inflammatory Pain: a Narrative Review. [PDF]

Maedica (Bucur)
Jafal NM, Stoleru S, Orban C, Fulga IG.
europepmc   +1 more source

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source