Results 221 to 230 of about 72,097 (314)
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu+4 more
wiley +1 more source
Peripherally Restricted Activation of Opioid Receptors Influences Anxiety-Related Behaviour and Alters Brain Gene Expression in a Sex-Specific Manner. [PDF]
Parkar N+7 more
europepmc +1 more source
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo+5 more
wiley +1 more source
Editorial: Opioids and opioid receptors in pain, addiction, and mood disorders. [PDF]
Qiu Y, Wang YJ.
europepmc +1 more source
Abstract Background Restless Legs Syndrome (RLS) is a neurological disorder reported to be associated with impulsivity and impairments in interoception and emotional regulation. However, limited research has explored the combined influence of RLS severity, psychological factors, and chronotype on impulsive decision‐making and risk‐taking behavior in ...
Giacomo Carollo+5 more
wiley +1 more source
Study of Antidepressant Actions of Subanesthetic Nitrous Oxide: Importance of Adequate Blinding and Opioid Receptors. [PDF]
Gillman MA.
europepmc +1 more source
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar+4 more
wiley +1 more source
Total-body imaging of mu-opioid receptors with [11C]carfentanil in non-human primates. [PDF]
Hsieh CJ+7 more
europepmc +1 more source
ABSTRACT Introduction/Aims Pain is a recognized symptom of muscular dystrophy (MD), but little is known about prescription pain medications in this population. We describe pain experiences and pain medications prescribed for individuals with selected MDs using population‐based surveillance data collected by the Muscular Dystrophy Surveillance, Tracking,
Jonathan Suhl+9 more
wiley +1 more source