Results 231 to 240 of about 72,097 (314)

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism. [PDF]

Addict Neurosci
Bedard ML, Huang XP, Murray JG, Nowlan AC, Conley SY, Mott SE, Loyack SJ, Cline CA, Clodfelter CG, Dasgupta N, Krumm B, Roth BL, McElligott ZA.   +12 more
europepmc   +1 more source

Inhibitory Effects of NaCl and Guanyl-5'yl-imidodiphosphate (GppNHp) on (3H)Naloxone Binding to .KAPPA.-Opioid Receptors in Guinea Pig Cerebellum.

, 1993
Kumiko Ishige, M Makimura, Yukako Ιtο, Y. Murakoshi   +3 more
openalex   +2 more sources

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, EarlyView.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

The Role of the Mu Opioid Receptors of the Medial Prefrontal Cortex in the Modulation of Analgesia Induced by Acute Restraint Stress in Male Mice. [PDF]

Int J Mol Sci
Du Y, Zhao Y, Zhang A, Li Z, Wei C, Zheng Q, Qiao Y, Liu Y, Ren W, Han J, Sun Z, Hu W, Liu Z.   +12 more
europepmc   +1 more source

Opioid Analgesia Following Pediatric Adenotonsillectomy: A Randomized Clinical Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the safety and efficacy of nonopioid versus opioid pain management following adenotonsillectomy (AT) among pediatric patients. Study Design An open‐label randomized controlled trial. Setting Tertiary care children's hospital. Methods Patients aged 3 to 17 years undergoing AT were eligible.
Rachel L. Whelan, Jennifer L. McCoy, Leonid Mirson, Raymond C. Maguire, Noel Jabbour, Jeffrey P. Simons, Joseph E. Dohar, Dennis J. Kitsko, Amanda L. Stapleton, Allison B.J. Tobey, Cuneyt M. Alper, Amber D. Shaffer, Zachary R. Bennett, David H. Chi   +13 more
wiley   +1 more source

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex. [PDF]

Anesthesiology
Navratilova E, Qu C, Ji G, Neugebauer V, Guerrero M, Rosen H, Roberts E, Porreca F.   +7 more
europepmc   +1 more source

Steroids for Pediatric Adenotonsillectomy Pain—A Prospective Multicenter Randomized Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare postoperative caregiver‐reported pain control of two steroid regimens following pediatric adenotonsillectomy. Secondary objectives assessed differences in analgesic use, return to normal diet, caregiver calls, adverse effects, and emergency room (ER) visits. Study Design Prospective randomized pragmatic trial.
Kevin D. Pereira, Wiktoria A. Gocal, Anna V. Borodianski, Mary E. Williamson, Hengameh K. Behzadpour, Sonal Saraiya, Diego A. Preciado, Amal Isaiah   +7 more
wiley   +1 more source

Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Oxaliplatin‐induced peripheral neuropathy (OIPN) is a major clinical challenge because it leads to discontinuation of chemotherapy. Omeprazole, a proton pump inhibitor (PPI), has been shown to prevent OIPN in a rat model. Therefore, we aimed to test whether the concomitant use of a PPI reduces oxaliplatin discontinuation due to OIPN.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Hibiki Kudamatsu, Shunsuke Fujita, Mayako Uchida, Takaaki Yamada, Nobuaki Egashira, Ichiro Ieiri, Satoru Koyanagi, Shigehiro Ohdo, Takao Shimazoe, Daisuke Kobayashi   +14 more
wiley   +1 more source

Who Gets Referred to School‐Based Trauma Treatment? A Descriptive Analysis of Bounce Back and Support for Students Exposed to Trauma

Psychology in the Schools, EarlyView.
ABSTRACT This study describes one district's experience having counselors deliver, for the first time, a school‐based treatment to address student trauma symptoms. After their initial training, school counselors rated Bounce Back (K‐5th grade) and Support for Students Exposed to Trauma (5th−12th grade) as highly acceptable and anticipated a positive ...
Yourdanos Bekele, Kristin Scardamalia, Sharon A. Hoover, Cindy M. Schaeffer   +3 more
wiley   +1 more source

Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine. [PDF]

Neuropsychopharmacology
Levinstein MR, Michaelides M.
europepmc   +1 more source