Results 241 to 250 of about 135,910 (355)

Complications Following Bilateral Salpingectomy by Indication: Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Assess the short‐term surgical outcomes of bilateral salpingectomy performed as a standalone procedure, focusing on complication rates by surgical indication and age group. Design Retrospective population‐based cohort. Setting British Columbia, Canada, from January 1st, 2008, to December 31st, 2022.
Alexandra Lukey, Helena Abreu do Valle, A. Fuchsia Howard, Celeste Leigh Pearce, David G. Huntsman, Janice S. Kwon, Jessica N. McAlpine, Michael R. Law, Paramdeep Kaur, Rafael Meza, Gillian E. Hanley   +10 more
wiley   +1 more source

Presynaptic Mu Opioid Receptors Suppress the Functional Connectivity of Ventral Tegmental Area Dopaminergic Neurons with Aversion-Related Brain Regions. [PDF]

J Neurosci
Wu Y, Perez-Rosello T, Awatramani R, Surmeier DJ.   +3 more
europepmc   +1 more source

Structure–Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the “Message-Address Concept” To Comprehend Their Functional Conversion

, 2018
Samuel Obeng, Huiqun Wang, Abdulmajeed M. Jali, David L. Stevens, Hamid I. Akbarali, William L. Dewey, Dana E. Selley, Yan Zhang   +7 more
openalex   +2 more sources

“It's such a terrible drug”: Narratives of fentanyl dealers amid the opioid overdose crisis

Criminology, EarlyView.
Abstract The fentanyl‐fueled overdose crisis is historically lethal, yet the voices of those who sell fentanyl remain understudied. While research has focused extensively on people who use drugs (PWUD), the perspectives of people who sell fentanyl (PWSF) are largely absent from academic and policy discussions. This study draws on 87 in‐depth interviews
Brittney M. Schwehr, Sandra M. Bucerius
wiley   +1 more source

κ-Opioid Receptor Stimulation Improves Endothelial Function in Hypoxic Pulmonary Hypertension

, 2013
Qi Wu, Haiyan Wang, Juan Li, Peng Zhou, Qiulin Wang, Lei Zhao, Rong Fan, Yuemin Wang, Xuezeng Xu, Dinghua Yi, Shiqiang Yu, Jianming Pei   +11 more
openalex   +2 more sources

Toronto's drug policy paradox: Harm reduction sites and drug police occurrences in Toronto neighborhoods (1992–2020)

Criminology, EarlyView.
Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley   +1 more source

The Identification of Opioid Receptors and Peptide Precursors in Human DRG Neurons Expressing Pain-Signaling Molecules Confirms Their Potential as Analgesic Targets. [PDF]

Cells
Mousa SA, Shaqura M, Tafelski S, Wandrey JD, Celik Ö, Treskatsch S, Schäfer M.   +6 more
europepmc   +1 more source

Cluster‐Randomized Trials in Emergency Care Research

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective Cluster‐randomized trials (also called group‐randomized trials) are increasingly common in emergency care research. In such trials, groups of participants are allocated to different interventions based on naturally occurring “clusters,” such as clinics, hospitals, or emergency medical services agencies. In this methodological review,
Howard S. Kim, Jacob M. Schauer, Jody D. Ciolino   +2 more
wiley   +1 more source

Ketamine and Major Ketamine Metabolites Function as Allosteric Modulators of Opioid Receptors. [PDF]

Mol Pharmacol
Gomes I, Gupta A, Margolis EB, Fricker LD, Devi LA.   +4 more
europepmc   +1 more source

The Financial Sustainability of Programs to Initiate Medications for Opioid Use Disorder in Emergency Department Settings

Academic Emergency Medicine, EarlyView.
ABSTRACT Background The US is experiencing an epidemic of opioid misuse and mortality. Effective treatments are available, including medications for opioid use disorders (MOUD), but they are greatly underused due to a variety of barriers. In response, some US hospitals have established programs to identify emergency department (ED) patients with opioid
Dominic Hodgkin, Cindy Parks Thomas, Margot T. Davis, Jennifer J. Wicks, Shelly F. Greenfield, Zachary F. Meisel, Constance M. Horgan   +6 more
wiley   +1 more source