Results 241 to 250 of about 72,097 (314)

Preoperative spinal education for lumbar spinal stenosis (POSE‐LSS): A qualitative analysis of patient experiences

open access: yesPM&R, EarlyView.
Abstract Background Surgical intervention for lumbar spinal stenosis (LSS) is common and associated with high rates of postoperative side effects or complications. Prehabilitation programs aim to reduce postoperative complications and enhance outcomes.
James E. Eubanks Jr   +7 more
wiley   +1 more source

Effectiveness of a multimodal physiotherapy program in fighter pilots with flight‐related neck pain: A randomized controlled trial

open access: yesPM&R, EarlyView.
Abstract Background Flight‐related neck pain constitutes a clinical entity related to the performance, occupational health, and flight safety of fighter pilots. Objective To investigate whether a multimodal physiotherapy program combining supervised motor control exercises with laser‐guided feedback and interferential current therapy with ...
Carlos Fernández‐Morales   +4 more
wiley   +1 more source

The effect of the irreversible μ-opioid receptor antagonist clocinnamox on morphine potency, receptor binding and receptor mRNA

open access: hybrid, 1995
Kawa Chan   +5 more
openalex   +1 more source

Opioid consumption after lower limb amputation in Medicare beneficiaries

open access: yesPM&R, EarlyView.
Abstract Background Despite targeted national quality improvement initiatives, opioid prescription and use patterns after lower limb amputation are not well studied. Objective To determine risk factors associated with extended opioid use and rates of high‐risk opioid prescribing after lower limb amputation. Design and setting A retrospective population‐
Alexander N. Khouri   +5 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Effects of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation: A Multicenter, Randomized Controlled Study

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Objective The objective of this study was to investigate the efficacy of transcutaneous auricular vagal nerve stimulation (taVNS) in adult patients with chronic constipation. Design Consecutive patients who met the Rome IV criteria for chronic constipation were enrolled and randomly assigned to either the taVNS group or the sham‐taVNS group ...
Tangyi Liu   +19 more
wiley   +1 more source

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