Results 281 to 290 of about 2,447,948 (384)

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism. [PDF]

Addict Neurosci
Bedard ML, Huang XP, Murray JG, Nowlan AC, Conley SY, Mott SE, Loyack SJ, Cline CA, Clodfelter CG, Dasgupta N, Krumm B, Roth BL, McElligott ZA.   +12 more
europepmc   +1 more source

Inhibitory Effects of NaCl and Guanyl-5'yl-imidodiphosphate (GppNHp) on (3H)Naloxone Binding to .KAPPA.-Opioid Receptors in Guinea Pig Cerebellum.

, 1993
Kumiko Ishige, M Makimura, Yukako Ιtο, Y. Murakoshi   +3 more
openalex   +2 more sources

Environmental life cycle of fentanyl: From the cradle to an unknown grave

Journal of Environmental Quality, EarlyView.
Abstract The lack of available information on the presence and persistence of fentanyl in the environment is a significant gap in the technical literature. Although the origins of the opioid in the environment are well‐known because they follow the same pathways of other drug‐related environmental contaminants, the downstream effects of fentanyl in the
Deseree J. Reid, Kaizad F. Patel, Angela M. Melville, Vanessa L. Bailey, Kristin M. Omberg, Loreen R. Lamoureux   +5 more
wiley   +1 more source

The Role of the Mu Opioid Receptors of the Medial Prefrontal Cortex in the Modulation of Analgesia Induced by Acute Restraint Stress in Male Mice. [PDF]

Int J Mol Sci
Du Y, Zhao Y, Zhang A, Li Z, Wei C, Zheng Q, Qiao Y, Liu Y, Ren W, Han J, Sun Z, Hu W, Liu Z.   +12 more
europepmc   +1 more source

Butorphanol or a Combination of Ketamine and Xylazine Do Not Interfere With Arrhythmogenic Parameters in Agoutis (Dasyprocta prymnolopha) Obtained Through High‐Resolution Electrocardiogram

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Introduction/Objectives: Agoutis is a medium‐sized wild rodent with potential for use as an experimental model. This study aimed to evaluate physiological parameters of arrhythmogenesis in this species, by HR‐ECG and VCG techniques, under physical and pharmacological containment (ketamine‐xylazine and butorphanol). Materials and methods: Eight
Charlys Rhands Coelho de Moura, Hermínio José da Rocha Neto, Regina Lucia dos Santos Silva, Nayla Maria da Silva Rezende Amorim, José Lindenberg Rocha Sarmento, Miguel Ferreira Cavalcante Filho, Wanderson Gabriel Gomes de Melo, Dayseanny de Oliveira Bezerra, Maria Acelina Martins Carvalho, Napoleão Martins Argolo Neto   +9 more
wiley   +1 more source

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex. [PDF]

Anesthesiology
Navratilova E, Qu C, Ji G, Neugebauer V, Guerrero M, Rosen H, Roberts E, Porreca F.   +7 more
europepmc   +1 more source

Systematic in‐hospital screening and treatment for osteoporosis in a geriatric population with hip fractures

Journal of Hospital Medicine, EarlyView.
Abstract Background Low‐trauma fractures of the hip signify osteoporosis and increase the risk of a second fracture. However, screening for secondary osteoporosis and initiating osteoporosis treatment can be challenging in a geriatric population.
Jeppe B. Rosenbæk, Line B. Dalgaard, Anne Grauballe, Stella J. Wilfred, Mikkel W. Ibsen, Lene R. Madsen   +5 more
wiley   +1 more source

The Role of Proton Magnetic Resonance Spectroscopy in Neonatal and Fetal Brain Research

Journal of Magnetic Resonance Imaging, EarlyView.
The biochemical composition and structure of the brain are in a rapid change during the exuberant stage of fetal and neonatal development. 1H‐MRS is a noninvasive tool that can evaluate brain metabolites in healthy fetuses and infants as well as those with neurological diseases.
Steve C.N. Hui, Nickie Andescavage, Catherine Limperopoulos   +2 more
wiley   +1 more source

Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine. [PDF]

Neuropsychopharmacology
Levinstein MR, Michaelides M.
europepmc   +1 more source

The effectiveness of oral and sublingual ketamine in pain management: a systematic review and meta‐analysis

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Aim The aim of this study was to undertake a systematic review and meta‐analysis to determine the effectiveness of oral and sublingual ketamine in pain management. Data Sources A systematic search was conducted utilising four databases: MEDLINE, CINAHL, Embase, and Web of Science. Study Selection The study included randomised controlled trials
Stephanie Elizabeth Harris, Jeremy Szmerling, Diarna Abbott, Enwu Liu, John Oldroyd   +4 more
wiley   +1 more source