Results 311 to 320 of about 135,910 (355)
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2002
Abstract Opioid receptors are the targets of analgesic compounds, of which the alkaloid from opium, morphine, remains the most widely used for relieving severe pain. The existence of opioid receptors was first postulated in the 1950s, and established in 1973 by three groups independently (Pert and Snyder 1973; Simon et al .
François Cesselin, Michel Hamon
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Abstract Opioid receptors are the targets of analgesic compounds, of which the alkaloid from opium, morphine, remains the most widely used for relieving severe pain. The existence of opioid receptors was first postulated in the 1950s, and established in 1973 by three groups independently (Pert and Snyder 1973; Simon et al .
François Cesselin, Michel Hamon
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Historical review: Opioid receptors
Trends in Pharmacological Sciences, 2003A historical review of the early phases of molecular investigations of opioid receptors is presented. The 'modern' era of molecular studies of neurotransmitter and drug receptor research commenced in the 1970s with the identification of receptors using ligand binding techniques. These findings had several ramifications.
Solomon H, Snyder, Gavril W, Pasternak
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Oligomerization of opioid receptors
Methods, 2002Opioid receptors belong to the family of G-protein-coupled receptors characterized by their seven transmembrane domains. The activation of these receptors by agonists such as morphine and endogenous opioid peptides leads to the activation of inhibitory G-proteins followed by a decrease in the levels of intracellular cAMP.
Ivone, Gomes +3 more
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Opioids, Receptors, and Immunity
1993The results achieved by those seeking to determine whether opioids and other drugs of abuse can affect immunity are quite astonishing given the short period of time that research has focused on this area. Despite the fact that there is no longer any question that opioids produce a variety of effects on the immune system, the extent and significance of ...
M W, Adler +4 more
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Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000
M, Satoh, T, Seki, M, Minami
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M, Satoh, T, Seki, M, Minami
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Behavioral interventions alter urologists' opioid prescribing practices
Ca-A Cancer Journal for Clinicians, 2021exaly