Results 321 to 330 of about 2,576,885 (397)

Changing trends in drug overdose mortality in Spain, 2001–2022

Addiction, EarlyView.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné, Marta Donat, Juan Miguel Guerras, Gregorio Barrio, María José Belza, Julieta Politi, Enrique Regidor   +6 more
wiley   +1 more source

The Role of the Mu Opioid Receptors of the Medial Prefrontal Cortex in the Modulation of Analgesia Induced by Acute Restraint Stress in Male Mice. [PDF]

Int J Mol Sci
Du Y, Zhao Y, Zhang A, Li Z, Wei C, Zheng Q, Qiao Y, Liu Y, Ren W, Han J, Sun Z, Hu W, Liu Z.   +12 more
europepmc   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex. [PDF]

Anesthesiology
Navratilova E, Qu C, Ji G, Neugebauer V, Guerrero M, Rosen H, Roberts E, Porreca F.   +7 more
europepmc   +1 more source

A systematic review of reviews on comprehensive community initiatives to prevent or reduce alcohol and other drug harms

Addiction, EarlyView.
Abstract Background and Aims Comprehensive community initiatives (CCI) aimed at reducing or preventing alcohol or other drug (AOD) harms incorporate multiple initiatives delivered to whole communities to effect community‐level change on sociocultural and environmental factors.
Peter John Gates, Andrea C. Zocco, Sara Farnbach   +2 more
wiley   +1 more source

Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine. [PDF]

Neuropsychopharmacology
Levinstein MR, Michaelides M.
europepmc   +1 more source

Molecular Aspects of Opioid Receptors and Opioid Receptor Painkillers

, 2012
Yongye, Austin B., Martínez-Mayorga, Karina   +1 more
openaire   +1 more source

Sustained fentanyl exposure inhibits neuronal activity in dissociated striatal neuronal-glial cocultures through actions independent of opioid receptors.

J Neurophysiol
Yarotskyy V, Nass SR, Hahn YK, Contois L, McQuiston AR, Knapp PE, Hauser KF.   +6 more
europepmc   +1 more source

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Opioid receptors: drivers to addiction?

Nature Reviews Neuroscience, 2018
Emmanuel Darcq, Brigitte Kieffer
exaly   +2 more sources