Results 31 to 40 of about 2,459,745 (358)

Opioid Receptors in Psoriatic Skin: Relationship with Itch.

Acta Dermato-Venereologica, 2017
Psoriasis is an inflammatory immunogenetic skin disease, often accompanied by itch. Opioid receptors are known regulators of itch sensation in the central nervous system.
Piotr Kupczyk, A. Reich, M. Hołysz, M. Gajda, E. Wysokińska, A. Kobuszewska, Dmitry Nevozhay, B. Nowakowska, L. Strzadala, P. Jagodziński, J. Szepietowski   +10 more
semanticscholar   +1 more source

Estradiol and Mu opioid-mediated reward: The role of estrogen receptors in opioid use

Addiction Neuroscience, 2023
Opioid use and opioid use disorder are characterized by sex and gender differences, and some of these differences may be mediated by differences in the hormonal milieu within and across individuals.
Sarah B. Ethridge, Mark A. Smith
doaj  

Molecular and cellular mechanisms of the age-dependency of opioid analgesia and tolerance

Molecular Pain, 2012
The age-dependency of opioid analgesia and tolerance has been noticed in both clinical observation and laboratory studies. Evidence shows that many molecular and cellular events that play essential roles in opioid analgesia and tolerance are actually age-
Zhao Jing, Xin Xin, Xie Guo-xi, Palmer Pamela, Huang Yu-guang   +4 more
doaj   +1 more source

BmK-YA, an enkephalin-like peptide in scorpion venom. [PDF]

PLoS ONE, 2012
By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor
Yan Zhang, Junyan Xu, Zhiwei Wang, Xiuli Zhang, Xinmiao Liang, Olivier Civelli   +5 more
doaj   +1 more source

Solid Tumor Opioid Receptor Expression and Oncologic Outcomes: Analysis of the Cancer Genome Atlas and Genotype Tissue Expression Project

Frontiers in Oncology, 2022
BackgroundOpioid receptors are expressed not only by neural cells in the central nervous system, but also by many solid tumor cancer cells. Whether perioperative opioids given for analgesia after tumor resection surgery might inadvertently activate tumor
Amparo Belltall, Amparo Belltall, Sheila Zúñiga-Trejos, Iris Garrido-Cano, Iris Garrido-Cano, Pilar Eroles, Pilar Eroles, Maria Pilar Argente-Navarro, Maria Pilar Argente-Navarro, Donal J. Buggy, Donal J. Buggy, Oscar Díaz-Cambronero, Oscar Díaz-Cambronero, Oscar Díaz-Cambronero, Guido Mazzinari, Guido Mazzinari, Guido Mazzinari   +16 more
doaj   +1 more source

Delta-opioid receptor endocytosis in spinal cord after dermenkephalin activation

BMC Neuroscience, 2000
Background The delta(δ)-opioid receptors belong to the G protein-coupled receptors and in vitro studies have shown that δ-opioid receptors undergo an internalization process in response to agonist stimulation.
Gastard Myriam
doaj   +1 more source

Delta opioid receptors regulate temporoammonic-activated feedforward inhibition to the mouse CA1 hippocampus. [PDF]

PLoS ONE, 2013
The opioid system influences learning and memory processes. However, neural mechanisms underlying the modulation of hippocampal activity by opioid receptors remain largely unknown. Here, we compared how mu and delta receptors operate within the mouse CA1
Xavier Rezai, Brigitte L Kieffer, Michel J Roux, Dominique Massotte   +3 more
doaj   +1 more source

Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens

International Journal of Neuropsychopharmacology, 2015
Background: Chronic ethanol exposure reduces dopamine transmission in the nucleus accumbens, which may contribute to the negative affective symptoms associated with ethanol withdrawal.
J. Rose, Anushree N. Karkhanis, Rong Chen, D. Gioia, Marcelo F. Lopez, H. Becker, B. McCool, S. Jones   +7 more
semanticscholar   +1 more source

βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression

Frontiers in Physiology, 2023
Opioid medications are the mainstay of pain management but present substantial side-effects such as respiratory depression which can be lethal with overdose.
Jamil Danaf, Carolina da Silveira Scarpellini, Gaspard Montandon, Gaspard Montandon   +3 more
doaj   +1 more source

Ageism in Rheumatology: the Healthcare Professional's Perspective

Arthritis Care &Research, Accepted Article.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the healthcare professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact ...
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source