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Kappa Opioid Receptor Antagonists as Potential Therapeutics for Stress-Related Disorders.

Annual Review of Pharmacology and Toxicology, 2020
Exposure to stressful stimuli activates kappa opioid receptor (KOR) signaling, a process known to produce aversion and dysphoria in humans and other species. This endogenous opioid system is dysregulated in stress-related disorders, specifically in major
Moriah L. Jacobson, C. Browne, I. Lucki
semanticscholar   +3 more sources

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