Results 311 to 320 of about 714,581 (348)

Opioid system influences gut-brain axis: Dysbiosis and related alterations.

Pharmacological Research, 2020
Opiod drugs are widely used to treat chronic pain, but their misuse can lead to tolerance, dependence, and addiction and have created a significant public health problem.
L. Rueda-Ruzafa, F. Cruz, D. Cardona, Arik J. Hone, G. Molina-Torres, Nuria Sánchez-Labraca, P. Roman   +6 more
semanticscholar   +1 more source

Is South Africa being spared the global opioid crisis? A review of trends in drug treatment demand for heroin, nyaope and codeine-related medicines in South Africa (2012-2017).

The International journal on drug policy, 2020
INTRODUCTION South Africa has seen a sharp increase in treatment admission trends for opioids despite beliefs that rates of opioid use remain low and do not represent a major problem.
Nadine Harker, W. Lucas, R. Laubscher, S. Dada, B. Myers, C. Parry   +5 more
semanticscholar   +1 more source

Suicidal ideation and attempts following nonmedical use of prescription opioids and related disorder

Psychological Medicine, 2020
AbstractBackgroundSince 1999, the rate of fatal prescription opioid overdoses and of suicides has dramatically increased in the USA. These increases, which have occurred among similar demographic groups, have led to the hypothesis that the opioid epidemic contributed to increases in suicidal behavior, though the underlying association remains poorly ...
Julian Santaella-Tenorio, Silvia S. Martins, Magdalena Cerdá, Mark Olfson, Katherine M. Keyes   +4 more
openaire   +2 more sources

Racial/ethnic representation in opioid use disorder-related clinical trials

Journal of Substance Use and Addiction Treatment
Little is known about representation in trials aimed at addressing Opioid Use Disorder. This is a crucial issue given high mortality rates overall and substantial differences in death rates across racial/ethnic groups.We analyzed data from clinical trials, data on Census population, data on new admissions to treatment facilities with a diagnosis of ...
Daniel, Sledge, Bai Linh, Hoang
openaire   +2 more sources

Buprenorphine Treatment of Fentanyl-Related Opioid Use Disorder

The Primary Care Companion For CNS Disorders, 2022
Oluwole, Jegede, Suprit, Parida, Joao P, De Aquino   +2 more
openaire   +2 more sources

The Failing Cascade: Comorbid Post Traumatic- and Opioid Use Disorders.

Neuroscience and Biobehavioral Reviews, 2019
Opioid use disorder (OUD) is a mounting public health problem with substantial morbidity and mortality. Stress involvement in the course of OUD is generally accepted, but little is understood about the underlying neurobiological mechanisms in part due to
Igor Elman, D. Borsook
semanticscholar   +1 more source

Childhood Traumas, Attachment Styles and Related Clinical Factors in Opioid Use Disorder

Archives of Neuropsychiatry
The study aims to compare childhood traumas, attachment styles, impulsivity, and quality of life of Opioid Use Disorder (OUD) patients in remission with healthy controls and to reveal the relationships between these parameters.The study included one hundred patients diagnosed with OUD and one hundred healthy volunteers.
Müge, Topcuoğlu, Mustafa Nogay, Coşkun, Ali, Erdoğan, Burak, Kulaksızoğlu   +3 more
openaire   +2 more sources

Opioid agonist therapy for fentanyl-related opioid use disorder: a scoping review

Opioid use disorder is characterized by a pattern of opioid use that leads to clinically significant impairment or distress. Fentanyl, a synthetic opioid considerably more potent than morphine, is now the most common opioid found in post-modern toxicology in opioid-related deaths.
openaire   +1 more source

A Harm Reduction Framework for Integrated Treatment of Co-Occurring Opioid Use Disorder and Trauma-Related Disorders

Journal of Dual Diagnosis
The opioid epidemic has exposed a gulf in mental health research, treatment, and policy: Most patients with comorbid trauma-related disorder (TRD) and opioid use disorder (OUD) (TRD + OUD) remain undiagnosed or unsuccessfully treated for the combination of TRD symptoms and opioid use. TRD treatments tend to be psychotherapies that are not accessible or
Benjamin S. Israel, Annabelle M. Belcher, Julian D. Ford   +2 more
openaire   +2 more sources

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Ca-A Cancer Journal for Clinicians, 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel   +2 more
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