Prevalence and predictors of suicidality among adults initiating office-based buprenorphine [PDF]
Background Individuals who have substance use disorders may have an elevated risk of suicidality. This study sought to examine the prevalence of, and identify factors associated with, suicidality in adults with opioid use disorder (OUD) initiating office-
Michelle R. Lent+5 more
doaj +3 more sources
Comorbid opioid use is undertreated among forensic patients with schizophrenia [PDF]
Background Substance use disorders are associated with poorer clinical outcomes in patients with schizophrenia. There is no specific treatment for amphetamine or cannabis use disorder, but methadone and buprenorphine are used as replacement therapy in ...
Kristiina Kivimies+3 more
doaj +4 more sources
Association between recent overdose and chronic pain among individuals in treatment for opioid use disorder. [PDF]
Chronic pain increases risk for opioid overdose among individuals with opioid use disorder. The purpose of this study is to evaluate the relationship between recent overdose and whether or not chronic pain is active.
Sarah M Hartz+8 more
doaj +4 more sources
Stratified analyses of genome wide association study data reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is associated with opioid use in patients of Arabian descent [PDF]
Background Genome Wide Association Studies (GWAS) have been conducted to identify genes and pathways involved in development of opioid use disorder. This study extends the first GWAS of substance use disorder (SUD) patients from the United Arab Emirates (
Hiba Alblooshi+6 more
doaj +3 more sources
A state-level study of opioid use disorder treatment access and neonatal abstinence syndrome [PDF]
Background Adult opioid use and neonatal abstinence syndrome (NAS) are growing public health problems in the United States (U.S.). Our objective was to determine how opioid use disorder treatment access impacts the relationship between adult opioid use ...
Elizabeth R. Wolf+6 more
doaj +3 more sources
The current opioid epidemic is devastating to the lives of individuals, families, and communities, but there are effective treatment approaches available. Treatment that combines proven medications with behavioral therapies and other supports is giving many in North Carolina the opportunity to engage in successful recovery.
Smith Worth, Kenny House
openalex +4 more sources
A Comparison of Veterans with Problematic Opioid Use Identified through Natural Language Processing of Clinical Notes versus Using Diagnostic Codes [PDF]
Background: Electronic health records (EHRs) are a data source for opioid research. Opioid use disorder is known to be under-coded as a diagnosis, yet problematic opioid use can be documented in clinical notes. Objectives: Our goals were 1) to identify problematic opioid use from a full range of clinical notes; and 2) to compare the characteristics ...
Kupersmith, Joel+5 more
arxiv +2 more sources
Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that drive adverse emotional states and relapse. However, successful recovery is possible with appropriate treatment, although with a persisting propensity to relapse.
George F. Koob+9 more
+9 more sources
Opioid use disorder in pregnancy [PDF]
AbstractThe number of pregnant people affected by the opioid epidemic in the United States continues to rise. The following key aspects of opioid use disorder in pregnancy are explored through the progression of a pregnancy via a patient case: treatment options, treatment decisions, substance use screening, dosing modifications, and other aspects of ...
Mary Malebranche, Anshula Ambasta
+10 more sources
Comorbid Opioid Use Disorder in Body Dysmorphic Disorder
Introduction Body Dysmorphic Disorder (BDD) is a severe and common disorder that consists of distressing or impairing preoccupation with nonexistent or slight flaws in one’s physical appearance.
J. Kim+4 more
doaj +1 more source