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The molecular neurobiology and neuropathology of opioid use disorder
The number of people diagnosed with opioid use disorder has skyrocketed as a consequence of the opioid epidemic and the increased prescribing of opioid drugs for chronic pain relief. Opioid use disorder is characterized by loss of control of drug taking,
Christopher A. Blackwood, Jean Lud Cadet
doaj +1 more source
State-Level Economic Costs of Opioid Use Disorder and Fatal Opioid Overdose — United States, 2017
Approximately 47,000 persons in the United States died from an opioid-involved overdose in 2018 (1), and 2.0 million persons met the diagnostic criteria for an opioid use disorder in 2017 (2). The economic cost of the U.S.
Feijun Luo, Mengyao Li, C. Florence
semanticscholar +1 more source
Background: The opioid epidemic is a global tragedy even with current treatments, and a novel, safe, and effective treatment would be welcomed. We report here our findings from our second randomized controlled trial to evaluate unilateral transcranial ...
Fredric Schiffer +9 more
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Co-prevalence of Substance Use Disorders and Common AxisⅠDisorders in Yunnan's Drug Users [PDF]
Background Mental disorders in drug users have received increasing attention. However, there are no any epidemiologic data available in regard to substance use disorders (SUD) and other mental disorders in drug users in Yunnan, one region that is hit ...
ZHANG Guanbai, ZHENG Ling, YANG Liping, ZHOU Qin, WANG Fei, HE Liangze, CHENG Xuan, CHA Li, LI Xinyue
doaj +1 more source
Background Number of opiate users worldwide has doubled over the past decade, but not all of them are diagnosed with opioid use disorder. We aimed to identify the prevalence and risk factors for OUD after ten years of follow-up.
Saba Alvand +12 more
doaj +1 more source
Opioid use disorder (OUD) through prescription opioid misuse, heroin, and illicitly manufactured fentanyl use has increased dramatically in the past 20 years.
Julia Dickson-Gomez +5 more
semanticscholar +1 more source
Big data and predictive modelling for the opioid crisis: existing research and future potential
Summary: A need exists to accurately estimate overdose risk and improve understanding of how to deliver treatments and interventions in people with opioid use disorder in a way that reduces such risk.
Chrianna Bharat, BSc +3 more
doaj +1 more source
High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder
Key Points Question Is high-dose (>12 mg) buprenorphine induction safe and well tolerated in patients with untreated opioid use disorder who present to the emergency department?
A. Herring +9 more
semanticscholar +1 more source
OBJECTIVE:Some patients who are given opioids for pain could develop opioid use disorder. If it was possible to identify patients who are at a higher risk of opioid use disorder, then clinicians could spend more time educating these patients about the ...
Jenna Marie Reps +2 more
doaj +1 more source
Background Concurrent opioid and stimulant use is on the rise in North America. This increasing trend of use has been observed in the general population, and among people released from prison in British Columbia (BC), who face an elevated risk of ...
Heather Palis +6 more
doaj +1 more source

