Results 111 to 120 of about 166,726 (313)

Model Opioids Biosurveillance Strategy for Public Health Practice [PDF]

This document was developed by the APHL Opioids Biosurveillance Task Force (OBTF) with support from APHL staff and subject matter expertise provided by the US Centers for Disease Control and Prevention (CDC).

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Opioids VS Non-Opioids: Which is Best for Pain Management? [PDF]

, 2017
This presentation is an evidence-based project comparing the use of opioids and non-opioids. The title is: Opioids VS Non-opioids: Which is Best for Pain Management?
Robbins, Kelsey
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Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

British Journal of Clinical Pharmacology, EarlyView.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

Difficulties with prescribed opioids: a cross-sectional survey of primary care patients in England, United Kingdom [PDF]

Introduction:Knowledge of the potential for harm and adverse effects from long-term opioid medicines has led to reduced prescribing in recent years.
Reham M. Baamer, Moss, José, Wilson, Louise E., Roger D. Knaggs, Baamer, Reham M., José Moss, Boyd, Matthew J., Anthony J. Avery, Matthew J. Boyd, Louise E. Wilson, Avery, Anthony J., Thornley, Tracey, Tracey Thornley, Knaggs, Roger D.   +13 more
core   +2 more sources

Opioid endocrinopathy : a clinical problem in patients with chronic pain and long-term opioid treatment [PDF]

, 2010
Background:The use of strong opioids for treatment of noncancer chronic pain has increased. However, strong evidence for sustained pain relief and improved function is lacking.
Stridsberg, Mats,, Rhodin, Annica,, Gordh, Torsten,   +2 more
core   +1 more source

Editorial: Opioids and opioid-use disorders

Frontiers in Pharmacology, 2023
Giordano de Guglielmo, Marsida Kallupi, Andrea Cippitelli, Daniele Caprioli, Daniele Caprioli, Kabirullah Lutfy   +5 more
openaire   +4 more sources

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Organisational practices in postoperative opioid prescribing at discharge in UK NHS Day Surgery Units: the OPIOID-Discharge survey [PDF]

Background: In March 2025, the Medicines and Healthcare products Regulatory Agency published a drug safety update removing the indication of postoperative pain from the licence of prolongedrelease opioids and mandated discussing risks with patients. This
Lobo, Dileep N, Levy, Nicholas, Rockett, Mark, Grodzinski¹, Ben   +3 more
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Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source