Results 121 to 130 of about 186,280 (306)

Paediatric clonidine medication errors: Findings from a multicentre French study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard, Anthony Facile, Marion Lepelley, Morgane Cellier, Laurent Chouchana, Sophie Gautier, Ramy Azzouz, Thierry Vial, Annie‐Pierre Jonville‐Bera   +8 more
wiley   +1 more source

Non-analgesic effects of opioids: The interaction of opioids with bone and joints

, 2012
Opioid consumption is associated with a wide range of side effects. Potential interference of opioids with bone and joint activity has emerged in the last few years. Opioids increase the risk of fracture, especially in elderly patients. Moreover, opioids
DI BUSSOLO, ELEONORA, COLUZZI, FLAMINIA, MATTIA, Consalvo   +2 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Staying Safe When Taking Prescription Opioids [PDF]

Prescription opioids, such as oxycodone, morphine, codeine, and hydrocodone, are often used for short-term pain management, and it is important to know how to keep yourself safe when taking opioids prescribed by a doctor.
Murza, Gabriela, Hunt, Aaron, May, Amy, Ferrin, Alyssa, Hawks, Jenna   +4 more
core   +1 more source

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

British Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy, Mariagrazia Felisi, Adriana Ceci, Oscar Della Pasqua, on Behalf of the GAPP Consortium, Corinne Alberti, Donato Bonifazi, Adriana Ceci, Thomas G. de Leeuw, Saskia N. de Wildt, Mariagrazia Felisi, Florentia Kaguelidou, Enora Le Roux, Rebecca Lundin, Laura Mangiarini, Dick Tibboel   +15 more
wiley   +1 more source

Opioid endocrinopathy : a clinical problem in patients with chronic pain and long-term opioid treatment

, 2010
Background:The use of strong opioids for treatment of noncancer chronic pain has increased. However, strong evidence for sustained pain relief and improved function is lacking.
Stridsberg, Mats,, Rhodin, Annica,, Gordh, Torsten,, Annica Rhodin, Mats Stridsberg, Torsten Gordh   +5 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Exploring profile, effects and toxicity of novel synthetic opioids and classical opioids via Twitter: A qualitative study

Emerging Trends in Drugs, Addictions, and Health
Background and aims: Novel synthetic opioids’ use has been increasing over the last decade and the opioid epidemic has attributed to 70 % of drug-related deaths worldwide.
Abdullah Al-Hamid, Carys Tudor, Sulaf Assi   +2 more
doaj   +1 more source

The impact of opioids on cognitive abilities – balancing pain management and cognitive preservation: A narrative review [PDF]

Introduction: Opioids are fundamental for managing moderate to severe pain, but their use is associated with the risk of cognitive impairment. A key clinical challenge is distinguishing the iatrogenic effects of opioids from the negative impact of ...
Lidia Jurczenko, Alina Semianiuk, Karol Zagórski, Agnieszka Partyka, Partyka, Agnieszka, Zagórski, Karol, Mierniczek, Mateusz, Jurczenko, Lidia, Semianiuk, Alina   +8 more
core   +1 more source

Acute toxic leucoencephalopathy following protonitazene ingestion

British Journal of Clinical Pharmacology, EarlyView.
Background Distribution of illicit counterfeit alprazolam containing the highly potent synthetic opioid‐receptor agonist protonitazene recently resulted in a number of severe overdoses in Ireland. We report three cases that presented to our hospital, within 6 weeks of one another, following ingestion of illicitly‐sourced alprazolam.
Ruadhan O'Laoi, Holly Acton, Pierce Kavanagh, Isabelle Hunt, Niall Sheehy, Cormac Kennedy   +5 more
wiley   +1 more source