Results 131 to 140 of about 186,280 (306)
Postcaesarean section analgesia: are opioids still required?
, 2015 Purpose of review The use of opioids for postoperative pain relief after caesarean section is widely spread. Because of unwanted well known side-effects, alternative drugs and methods of pain relief have been introduced, either in addition to or instead ...
Huisjes, A +2 more
core +1 more source
Translational development of crisugabalin for neuropathic pain
British Journal of Clinical Pharmacology, EarlyView.Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João +5 more
wiley +1 more source
Pain and TherapyIntroduction Chronic low back pain (CLBP) affects over half a billion people worldwide. Current pharmacologic treatments, comprising mainly non-steroidal anti-inflammatory drugs and opioids, offer limited efficacy and pose significant risks, warranting ...
Winfried Meissner +4 more
doaj +1 more source
Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences
British Journal of Clinical Pharmacology, EarlyView.Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry +3 more
wiley +1 more source
Opioid treatment of opioid addiction
Australian Prescriber, 2013 Opioid-related problems, including addiction, are increasing in Australia and more medical practitioners are likely to have contact with such patients.
openaire +1 more source
, 2018 Opioids otherwise known as narcotics are derived from opium to treat pain What\u27s the problem? 1 in 4 people struggle with prescription opioid abuse More than 2 million people in the United States struggle with prescription opioid abuse Examples of ...
Campbell, Michelle
core
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Lisdexamfetamine, a long‐acting stimulant for attention‐deficit hyperactivity disorder (ADHD), has experienced widespread shortages in Australia since late 2023, raising concerns about treatment continuity and shifts in stimulant use patterns.
Jack Janetzki +4 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
BMEMat, EarlyView.A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song +10 more
wiley +1 more source