Results 251 to 260 of about 512,940 (405)

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

The Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub, Shen Cheng, Mohamed S. Fayed, James Fisher, Jillian Brooks, Elizabeth Seaquist, Anjali Kumar, Amir Moheet, Lynn Eberly, Lisa D. Coles   +9 more
wiley   +1 more source

A monoclonal antibody capable of modulating opioid binding to rat neural membranes.

, 1985
Jean M. Bidlack, RM Denton
openalex   +1 more source

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M. T. Sherwin, Anne van Rongen, Daniëlla W. E. Roofthooft, Sinno H. P. Simons, Dick Tibboel, Robert B. Flint, John N. van den Anker, Catherijne A. J. Knibbe   +11 more
wiley   +1 more source

Seeing the bigger picture: endogenous opioids mediate attentional broadening after reward receipt. [PDF]

Psychol Med
van Steenbergen H, Gable P, Fagan H, Molteni L, Midveris A, Huneke N.   +5 more
europepmc   +1 more source

Opioids Prescribed After Low-Risk Surgical Procedures in the United States, 2004-2012.

Journal of the American Medical Association (JAMA), 2016
H. Wunsch, D. Wijeysundera, M. Passarella, M. Neuman   +3 more
semanticscholar   +1 more source

Reversal of Fentanyl‐Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto‐Injector Versus Intranasal Naloxone

The Journal of Clinical Pharmacology, EarlyView.
Abstract As illegally made fentanyl and congeners continue to drive overdose deaths in the US, experts have called for stronger and longer‐lasting antagonists. A randomized, 4‐period, 2‐treatment crossover replicate‐design study in healthy moderately‐experienced opioid users (n = 24) evaluated the reversal of opioid‐induced respiratory depression (OIRD)
Alessandra Cipriano, Ellie He, Manjunath Shet, Glen Apseloff, Stephen C. Harris   +4 more
wiley   +1 more source

A national cohort study of long-term opioid prescription and sociodemographic and health care-related risk factors. [PDF]

Commun Med (Lond)
Krüger C, Franck J, Widing H, Hällgren J, Gissler M, Westman J.   +5 more
europepmc   +1 more source

Influences of analgesics on the opioid peptide system in the rat incisor pulp

, 1986
Masato Kuroi, Huei-Ling Chang, Tomoaki Kudo, Reizo Inoki   +3 more
openalex   +1 more source

In-vivo studies on kappa opioid receptors [PDF]

, 1986
Alan Cowan, Debra E. Gmerek
openalex   +1 more source

Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness.

Cochrane Database of Systematic Reviews, 2016
H. Barnes, Julie McDonald, N. Smallwood, R. Manser   +3 more
semanticscholar   +1 more source