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Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2005Abstract Opioid analgesic drugs mimic the actions of three groups of endogenous opioid peptides, the enkephalins, dynorphins and endorphins. Opioid receptors have been cloned and have been classified as OP 1 (delta), OP 2 (kappa), OP 3 (mu) and OP 4 (ORL-1). The first three correspond to the classical opioid receptors that mediate analgesia.
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Journal of Pain & Palliative Care Pharmacotherapy, 2004
Opioid analgesics are an irreplaceable component of pharmacotherapy of numerous pain-producing conditions. Clinicians and patients must contend with the imperfect nature of this class of drugs, trying to balance benefits and burdens on a continual basis. New literature related to evidence-based selection of opioids and the neurobiological phenomenon of
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Opioid analgesics are an irreplaceable component of pharmacotherapy of numerous pain-producing conditions. Clinicians and patients must contend with the imperfect nature of this class of drugs, trying to balance benefits and burdens on a continual basis. New literature related to evidence-based selection of opioids and the neurobiological phenomenon of
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2019
Despite many advances made in the field of interventional pain management in the past decades, pharmacological therapy often remains the core of the spine pain multimodal treatment. It represents an indispensable therapeutic tool, especially when more interventional methods either failed or are not indicated.
Yakov Vorobeychik +4 more
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Despite many advances made in the field of interventional pain management in the past decades, pharmacological therapy often remains the core of the spine pain multimodal treatment. It represents an indispensable therapeutic tool, especially when more interventional methods either failed or are not indicated.
Yakov Vorobeychik +4 more
openaire +2 more sources
The Basics of Opioids and Opioid Addiction
2019What are opioids? Opioids are a group of chemical compounds that can reduce pain, cause sensations of pleasure, and induce sleep. To have these and other effects on the human body, all opioids interact with specific receptors on the surface of cells called opioid...
Yngvild Olsen, Joshua M. Sharfstein
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Opioid Tolerance or Opioid Withdrawal?
Anesthesiology, 2013Sloan C. Youngblood, Mark J. Harbott
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Opioid Analgesics and Opioid Antagonists
1980By opioid is meant any drug, regardless of chemical structure, that acts like morphine. The term opioid is preferred to the older term, opiate, for two reasons: first, because opiate implies presence in or derivation from opium, which indeed contains the analgesic drugs morphine and codeine but also contains thebaine, a strong stimulant (convulsive ...
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