Results 321 to 330 of about 512,940 (405)

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

Epidemiology of poisoning in elderly Iranians: a narrative review with global context. [PDF]

Int J Emerg Med
Nemati A, Moshiri M, Gholami M, Talebi M, Etemad L, Talebi Doluee M.   +5 more
europepmc   +1 more source

The Opioid Epidemic

Delaware Journal of Public Health, 2017
openaire   +3 more sources

The choroid plexus water density

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose To quantify normative ranges and circadian variability of the choroid plexus (ChP) water density in healthy adults. Methods Actigraphy assessments of circadian activity were performed for 5 days in healthy participants (n = 15; age = 28.5 ± 6.5 years) and subsequently participants underwent repeated, high spatial resolution proton ...
Abigail R. Dubois, Maeve Curtin, Kilian Hett, Melanie Leguizamon, Alexander K. Song, Maria Garza, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue   +8 more
wiley   +1 more source

Naloxone Disparities in Adolescents: Access Laws Are Not Enough. [PDF]

J Pediatr Pharmacol Ther
Habermann S, Mazer-Amirshahi M, Toce MS.
europepmc   +1 more source

Test–Retest Reliability of Perception Threshold Estimation in Small Cutaneous Nerve Fibers: A Methodological Investigation

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Nerve excitability testing of small cutaneous nerve fibers has been proposed as a new tool for investigating the underlying mechanisms of small fiber neuropathy. These assessments may be performed using perception threshold tracking with pin‐electrodes that preferentially activate small cutaneous nerve fibers.
Helena Brøckner, Sarah Nygaard Jensen, Kristian Hennings, Carsten Dahl Mørch   +3 more
wiley   +1 more source

Co-prescribing of antidepressants and opioids for non-cancer pain in England, 2010-2019: a descriptive study using CPRD primary care electronic health records. [PDF]

BMC Prim Care
Butler J, Joseph RM, Coupland C, Knaggs RD, Avery AJ, Morriss R, Butler D, Gerrard L, Waldram D, Jack RH.   +9 more
europepmc   +1 more source

Correlates of Positive Response to Therapeutic Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims The objective of this study was to assess the duration and clinical correlates of positive response in interstitial cystitis/bladder pain syndrome patients undergoing therapeutic bladder hydrodistension (HOD) or HOD with electrofulguration (for those with Hunner lesions).
Dylan T. Wolff, Carl D. Langefeld, Julie T. Call, Gopal Badlani, Robert J. Evans, Stephen J. Walker   +5 more
wiley   +1 more source

The role of prescribed opioids in Norwegian overdose deaths in 2005-2021. [PDF]

Eur J Clin Pharmacol
Edvardsen HME, Clausen T, Bogstrand ST, Skurtveit S.   +3 more
europepmc   +1 more source