Results 341 to 350 of about 512,940 (405)
Astrocytes and Astrocyte-Derived Extracellular Conduits in Opiate-Mediated Neurological Disorders. [PDF]
CellsRay S, Datta S, Saha A, Sil S.
europepmc +1 more source
CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016
MMWR Recommendations and Reports, 2016 This guideline provides recommendations for primary care clinicians who are prescribing opioids for chronic pain outside of active cancer treatment, palliative care, and end-of-life care.
Roger Chou
exaly +5 more sources
Opioids and the immune system – friend or foe
British Journal of Pharmacology, 2018 Heike L Rittner
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Current Issues in the Use of Opioids for the Management of Postoperative Pain: A Review.
JAMA Surgery, 2021Importance Uncontrolled and indiscriminate prescribing of opioids has led to an opioid crisis that started in North America and spread throughout high-income countries.
P. Macintyre +3 more
semanticscholar +1 more source
Surgical Neurology, 2007
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (
C, Zöllner, C, Stein
openaire +4 more sources
Opioids are the most effective and widely used drugs in the treatment of severe pain. They act through G protein-coupled receptors. Four families of endogenous ligands (opioid peptides) are known. The standard exogenous opioid analgesic is morphine. Opioid agonists can activate central and peripheral opioid receptors. Three classes of opioid receptors (
C, Zöllner, C, Stein
openaire +4 more sources
Addiction, 2020
AIMS To examine trends and recent changes in non-fatal and fatal stimulant overdose rates with and without opioids to improve the descriptive characterization of the US overdose epidemic. DESIGN Secondary analysis of non-fatal (2006-16) and fatal (2006-
B. Hoots +2 more
semanticscholar +1 more source
AIMS To examine trends and recent changes in non-fatal and fatal stimulant overdose rates with and without opioids to improve the descriptive characterization of the US overdose epidemic. DESIGN Secondary analysis of non-fatal (2006-16) and fatal (2006-
B. Hoots +2 more
semanticscholar +1 more source
Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2008Abstract The opioid system comprises four receptor subtypes: μ (MOP), κ (KOP), δ (DOP) (i.e. the so-called ‘classical' opioid receptors) and the more recently identified nociceptin/orphanin FQ peptide (N/OFQ) receptor (NOP). Selective endogenous peptides, typically cleaved from larger precursor proteins, have been identified for all subtypes.
McDonald, J, Lambert, DG
openaire +4 more sources