Results 361 to 370 of about 512,940 (405)
Opioid receptors and endogenous opioid peptides [PDF]
Medicinal Research Reviews, 1991 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2019Abstract Opioids are effective in acute and cancer pain management and have increasingly been prescribed in chronic non-cancer pain despite concerns regarding long-term use and lack of efficacy. Opioid actions are via G protein coupled receptors, the activation of which leads to a variety of physiological consequences including analgesia. Prescribing
Helen Laycock, Carston Bantel
openaire +2 more sources
Opioids and Opioid Receptors in Peripheral Tissues
Scandinavian Journal of Gastroenterology, 1987Opioid peptides belonging to the enkephalin, beta-endorphin or dynorphin family, acting on specific opiate receptors may be found in peripheral tissues. Enkephalins have a widespread peripheral distribution, while beta-endorphin and dynorphin may be found locally in the enteric nervous system.
Thomas Hedner, Jean Cassuto
openaire +2 more sources
Opioids, opioid receptors, and the immune response
Drug and Alcohol Dependence, 2001It is now clear that opioid receptors participate in the function of the cells of the immune system, and evidence suggests that opioids modulate both innate and acquired immune responses. We review literature here which establishes that mu-, kappa-, and delta-opioid compounds alter resistance to a variety of infectious agents, including the Human ...
Lois McCarthy +4 more
openaire +3 more sources
Clinical Pharmacology & Therapeutics, 2007
Opioids are used for acute and chronic pain and dependency. They have a narrow therapeutic index and large interpatient variability in response. Genetic factors regulating their pharmacokinetics (metabolizing enzymes, transporters) and pharmacodynamics (receptors and signal transduction elements) are contributors to such variability.
Somogyi, A., Barratt, D., Coller, J.
openaire +4 more sources
Opioids are used for acute and chronic pain and dependency. They have a narrow therapeutic index and large interpatient variability in response. Genetic factors regulating their pharmacokinetics (metabolizing enzymes, transporters) and pharmacodynamics (receptors and signal transduction elements) are contributors to such variability.
Somogyi, A., Barratt, D., Coller, J.
openaire +4 more sources
Opioid receptors and opioid pharmacodynamics
2005Abstract Opioids have a long and rich pharmacology. They are widely used throughout medicine and have been invaluable. However, they come with problems, including side effects such as constipation, respiratory depression and sedation, as well as the potential of abuse.
Mellar P Davis, Gavril W Pasternak
openaire +1 more source
Opioid mechanisms and opioid drugs
Anaesthesia & Intensive Care Medicine, 2005Abstract Opioid analgesic drugs mimic the actions of three groups of endogenous opioid peptides, the enkephalins, dynorphins and endorphins. Opioid receptors have been cloned and have been classified as OP 1 (delta), OP 2 (kappa), OP 3 (mu) and OP 4 (ORL-1). The first three correspond to the classical opioid receptors that mediate analgesia.
openaire +2 more sources
Journal of Pain & Palliative Care Pharmacotherapy, 2004
Opioid analgesics are an irreplaceable component of pharmacotherapy of numerous pain-producing conditions. Clinicians and patients must contend with the imperfect nature of this class of drugs, trying to balance benefits and burdens on a continual basis. New literature related to evidence-based selection of opioids and the neurobiological phenomenon of
openaire +2 more sources
Opioid analgesics are an irreplaceable component of pharmacotherapy of numerous pain-producing conditions. Clinicians and patients must contend with the imperfect nature of this class of drugs, trying to balance benefits and burdens on a continual basis. New literature related to evidence-based selection of opioids and the neurobiological phenomenon of
openaire +2 more sources