Results 71 to 80 of about 238,276 (229)

Association of Opioids and Sedatives with Increased Risk of In-Hospital Cardiopulmonary Arrest from an Administrative Database. [PDF]

PLoS ONE, 2016
BACKGROUND:While opioid use confers a known risk for respiratory depression, the incremental risk of in-hospital cardiopulmonary arrest, respiratory arrest, or cardiopulmonary resuscitation (CPRA) has not been studied.
Frank J Overdyk, Oonagh Dowling, Joseph Marino, Jiejing Qiu, Hung-Lun Chien, Mary Erslon, Neil Morrison, Brooke Harrison, Albert Dahan, Tong J Gan   +9 more
doaj   +1 more source

Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision‐Making and Polygenic Embryo Screening

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Polygenic risk scores (PRS) estimate individuals' genetic risk for developing multifactorial conditions. Recent genome‐wide association studies have enabled development of psychiatric PRS, which hold potential to streamline diagnosis and treatment of psychiatric conditions.
Lauren A. Ginn, Amanda R. Merner, Page M. Trotter, Kaitlynn P. Craig, Abigail C. Martinez, Ana Lucía Battaglino, Dorit Barlevy, Daphne M. Ayton, Takahiro Soda, Eric A. Storch, Gabriel Lázaro‐Muñoz, Stacey Pereira   +11 more
wiley   +1 more source

Neuropsychiatric manifestations due to anticholinergic agents and anabolic steroids ingestion: A case series and literature review

Neuropsychopharmacology Reports
Anticholinergic toxicity is a common occurrence in the emergency room, making it crucial for emergency clinicians to have a good understanding of this toxidrome.
Homa Talabaki, Mahkameh Soltani, Ali Abbasi, Vahid Sharifi, Narges Salehi, Zakaria Zakariaei   +5 more
doaj   +1 more source

Naloxone Administration Route in Opioid Overdose: A Review of Vermont EMS Data [PDF]

, 2017
Objective: Emergency Medical System (EMS) personnel administer the direct opioid antagonist naloxone in cases of opioid overdose via intramuscular (IM), intravenous (IV), subcutaneous (SQ), intraosseous (IO), or intranasal (IN) routes. Some early studies
LaMonda, Chris, MPH, O\u27Keefe, Michael, Sacco, Alden York, MPH, Trabulsy, Mario, MD, Wolfson, Daniel, MD   +4 more
core   +1 more source

Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]

, 2019
The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G., Mohler, George, Ray, Bradley   +2 more
core   +1 more source

Auditory Hyperresponsivity in Chronic Back Pain: A Randomized Controlled Trial of Pain Reprocessing Therapy

Annals of Neurology, EarlyView.
Objective Heightened sensitivity to noxious stimulation is a hallmark of chronic pain. Emerging evidence suggests heightened unpleasantness to non‐noxious (eg, auditory) aversive stimulation also characterizes chronic pain, but its magnitude, neural mechanisms, and treatment modifiability remain unknown.
Alina E. C. Panzel, Christian Büchel, Andrew Leroux, Tor D. Wager, Yoni K. Ashar   +4 more
wiley   +1 more source

Immunologic Profiling Suggests an Association Between Treg Cell Dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Pain is the hallmark symptom of osteoarthritis (OA), and its biologic drivers remain poorly understood. Although the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular Treg cells, is not well understood.
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Incidence and Predictive Factors for Prolonged Use of Opioid Medication After Foot and Ankle Surgery

Foot & Ankle Orthopaedics, 2018
Category: Other Introduction/Purpose: The purpose of this study is to evaluate the incidence and factors predictive for patients’ needs for opioid pain medication longer than 2 weeks after orthopaedic foot/ankle surgery in a single surgeon’s practice at ...
Jamal Ahmad MD
doaj   +1 more source

The Opioid Crisis in Rural and Small Town America [PDF]

, 2018
In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas.
Monnat, Shannon M, Rigg, Khary K
core   +1 more source

Stigma as a fundamental hindrance to the United States opioid overdose crisis response. [PDF]

, 2019
Alexander Tsai and co-authors discuss the role of stigma in responses to the US opioid ...
Barnett, Michael L, Beletsky, Leo, Keyes, Katherine M, Kiang, Mathew V, McGinty, Emma E, Smith, Laramie R, Strathdee, Steffanie A, Tsai, Alexander C, Venkataramani, Atheendar S, Wakeman, Sarah E   +9 more
core   +2 more sources