Commentary: Opium Alkaloids in Harvested and Thermally Processed Poppy Seeds [PDF]
Frontiers in Chemistry, 2021 Daria Kleinmeier +2 more
doaj +2 more sources
DNA methylation orchestrates secondary metabolite biosynthesis and transport in Papaver somniferum. [PDF]
PLoS ONEBackgroundPapaver somniferum (opium poppy) is a major source of benzylisoquinoline alkaloids (BIAs), including pharmaceutically important compounds such as morphine and noscapine.
Tuba Aksoylu, Mine Turktas
doaj +2 more sources
Frontiers in Plant ScienceBenzylisoquinoline alkaloids (BIAs) produced in opium poppy have been evidenced to heal patients suffering from various diseases. They, therefore, hold an integral position in the herbal drug industry.
Zahra Aghaali +3 more
doaj +3 more sources
Concentrations of the Opium Alkaloids Morphine, Codeine, and Thebaine in Poppy Seeds are Reduced after Thermal and Washing Treatments but are Not Affected when Incorporated in a Model Baked Product. [PDF]
J Agric Food Chem, 2020 Shetge SA +4 more
europepmc +2 more sources
Update on Opium Alkaloids in Food: Exploring Their Occurrence, Effect of Culinary Processing and Advances in Analytical Methodologies. [PDF]
Compr Rev Food Sci Food SafABSTRACT Following the implementation of the new European legislation on opium alkaloids (OAs) in food in 2023, scientific research has focused on developing analytical methodologies to determine the presence of these compounds in different foods. However, health authorities continue to suggest further studies to evaluate the occurrence of main OAs and
Casado-Hidalgo G +2 more
europepmc +2 more sources
Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Int J Anal ChemHeroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M +4 more
europepmc +2 more sources
Nature Communications, 2022 Opium poppy accumulates alkaloids in the specialized cytoplasm of laticifers known as latex. Here the authors show that the binding of alkaloids to the abundant major latex proteins triggers quaternary structural modification that mediates a functional ...
Natali Ozber +8 more
doaj +1 more source
, 2021 Opium alkaloids, derived from crude Papaver somniferum L. plant, are potent analgesic drugs, but their use is limited because of dependence and withdrawal. Opium alkaloids activate the mesocorticolimbic dopaminergic system, which project from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex, and dopamine is critically ...
Jafarova, Demirkapu, Mahluga +1 more
openaire +3 more sources
Journal of Analytical Science and Technology, 2017 Background Thin layer chromatography (TLC) has been a conventional analytical method which is currently used for separation and detection of drugs in biological and non-biological samples.
Kimia Esmaiili +1 more
doaj +1 more source
Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]
, 2011 The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena +5 more
core +2 more sources