Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Int J Anal ChemHeroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M +4 more
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Bioactive Compounds in Nutraceutical and Functional Food for Good Human Health, 1969 Opium alkaloids, derived from crude Papaver somniferum L. plant, are potent analgesic drugs, but their use is limited because of dependence and withdrawal. Opium alkaloids activate the mesocorticolimbic dopaminergic system, which project from the ventral
F. Lembeck, K.-Fr. Sewing
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Modulation of Blood Lead Level and Liver Function Tests in Iranian Opium Users [PDF]
International Journal of Preventive MedicineBackground: Opium users are at risk of lead poisoning. Therefore, this study aimed to compare opium users with healthy controls in terms of blood lead levels (BLLs), blood biochemistry, and liver function tests.
Mohammad Reza Eskandarion +10 more
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Network-based identification of hub transcription factors associated with benzylisoquinoline alkaloid biosynthesis in Papaver somniferum [PDF]
Biochemistry and Biophysics ReportsPapaver somniferum L. (Opium poppy) is one of the world's most economically valuable medicinal plants, and it is the industrial source of essential compounds such as painkillers and other pharmecutical drugs.
Mahsa Eshaghi, Sajad Rashidi-Monfared
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Differences in Experimental Outcomes from Thermal Processing: The Case of Poppy Seeds and Opium Alkaloids. [PDF]
J Agric Food Chem, 2021 Fleischman GJ +3 more
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Reduction of Morphine During Baking? Response: Commentary: Opium Alkaloids in Harvested and Thermally Processed Poppy Seeds. [PDF]
Front Chem, 2021 Kuntz M, Golombek P, Lachenmeier DW.
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Determination of relative response factors of the opium alkaloids with HPLC-DAD [PDF]
Makedonsko Farmacevtski Bilten, 2012 In this work, a convenient method for determination of relative UV response factors (RRFs) of morphine, codeine, thebaine, oripavine, noscapine and papaverine by high performance liquid chromatography (HPLC) equipped with a diode array detector (DAD) was
Jelena Acevska +5 more
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Non-addictive opium alkaloids selectively induce apoptosis in cancer cells compared to normal cells. [PDF]
Daru, 2015 BackgroundCytotoxic effects of some of the members of papaveraceae family have been reported in Iranian folk medicine. Recent reports has indicated that alkaloids fraction of opium may be responsible for its cytotoxic effect; however, the mechanism of ...
Afzali M +6 more
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DNA methylation orchestrates secondary metabolite biosynthesis and transport in Papaver somniferum. [PDF]
PLoS ONEBackgroundPapaver somniferum (opium poppy) is a major source of benzylisoquinoline alkaloids (BIAs), including pharmaceutically important compounds such as morphine and noscapine.
Tuba Aksoylu, Mine Turktas
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Investigation of Alkaloids in Opium Poppy (Papaver somniferum L.) Varieties and Hybrids
Journal of Agricultural Sciences, 2021 This study aimed to investigate the proportions of morphine, thebaine, noscapine, codeine, oripavine and papaverine alkaloids in poppy varieties and hybrids. Nine parents and 36 hybrid lines were used in the trial.
Levent Yazici, Güngör Yılmaz
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