Results 21 to 30 of about 84,269 (200)

Determination of Opium Alkaloid Content in Poppy Seeds Using Liquid Chromatography Coupled with a Mass Spectrometer with a Time-of-Flight Analyzer (UPLC-TOF-HRMS) [PDF]

Foods
Opium poppy is a plant used in both the pharmaceutical and food industries. Substances found on the surface of dry poppy seeds belong to the group of opium alkaloids.
Agnieszka Zapaśnik, Adam Pierzgalski, Marcin Bryła   +2 more
doaj   +2 more sources

Unearthed opium: development of a UHPLC-MS/MS method for the determination of Papaver somniferum alkaloids in Daunian vessels

Frontiers in Chemistry, 2023
Introduction: The analysis of organic residue in ancient vessels to investigate early-age civilization habits is an important archeological application that needs advanced analytical methods. However, these procedures should meet inherent requisites such
Gabriele Favero, Camilla Montesano, Manuel Sergi   +2 more
exaly   +3 more sources

DNA methylation orchestrates secondary metabolite biosynthesis and transport in Papaver somniferum. [PDF]

PLoS ONE
BackgroundPapaver somniferum (opium poppy) is a major source of benzylisoquinoline alkaloids (BIAs), including pharmaceutically important compounds such as morphine and noscapine.
Tuba Aksoylu, Mine Turktas
doaj   +2 more sources

Concentrations of the Opium Alkaloids Morphine, Codeine, and Thebaine in Poppy Seeds are Reduced after Thermal and Washing Treatments but are Not Affected when Incorporated in a Model Baked Product [PDF]

Journal of Agricultural and Food Chemistry, 2020
Jessica Cooperstone, Michael P Dzakovich, Benjamin Redan   +2 more
exaly   +2 more sources

Update on Opium Alkaloids in Food: Exploring Their Occurrence, Effect of Culinary Processing and Advances in Analytical Methodologies. [PDF]

Compr Rev Food Sci Food Saf
ABSTRACT Following the implementation of the new European legislation on opium alkaloids (OAs) in food in 2023, scientific research has focused on developing analytical methodologies to determine the presence of these compounds in different foods. However, health authorities continue to suggest further studies to evaluate the occurrence of main OAs and
Casado-Hidalgo G, Morante-Zarcero S, Sierra I.   +2 more
europepmc   +2 more sources

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]

Int J Anal Chem
Heroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M, Baig Y, Naseer A, Nardiello D, Quinto M.   +4 more
europepmc   +2 more sources

Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation

Nature Communications, 2022
Opium poppy accumulates alkaloids in the specialized cytoplasm of laticifers known as latex. Here the authors show that the binding of alkaloids to the abundant major latex proteins triggers quaternary structural modification that mediates a functional ...
Natali Ozber, Samuel C. Carr, Jeremy S. Morris, Siyu Liang, Jacinta L. Watkins, Kristian M. Caldo, Jillian M. Hagel, Kenneth K. S. Ng, Peter J. Facchini   +8 more
doaj   +1 more source

Opium Alkaloids

, 2021
Opium alkaloids, derived from crude Papaver somniferum L. plant, are potent analgesic drugs, but their use is limited because of dependence and withdrawal. Opium alkaloids activate the mesocorticolimbic dopaminergic system, which project from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex, and dopamine is critically ...
Mahluga Jafarova Demirkapu, Hasan Raci Yananli   +1 more
openaire   +2 more sources

Comparative verification study of silica gel-coated TLC and HPTLC plates’ performances in separation of opium alkaloids on the basis of their physicochemical properties

Journal of Analytical Science and Technology, 2017
Background Thin layer chromatography (TLC) has been a conventional analytical method which is currently used for separation and detection of drugs in biological and non-biological samples.
Kimia Esmaiili, Seyed Vahid Shetab-Boushehri   +1 more
doaj   +1 more source