Results 101 to 110 of about 40,625 (235)

BiP prevents rod opsin aggregation

Molecular Biology of the Cell, 2012
Mutations in rod opsin—the light-sensitive protein of rod cells—cause retinitis pigmentosa. Many rod opsin mutations lead to protein misfolding, and therefore it is important to understand the role of molecular chaperones in rod opsin biogenesis. We show that BiP (HSPA5) prevents the aggregation of rod opsin.
Athanasiou, D., Kosmaoglou, M., Kanuga, N., Novoselov, S., Paton, A., Paton, J., Chapple, J., Cheetham, M.   +7 more
openaire   +3 more sources

Retinal Dysplasia Mimicking Retinoblastoma. [PDF]

, 2012
Retinal dysplasia represents a congenital disorder characterized by abnormal proliferation of retinal tissue causing leukocoria. We present a case of an infant with bilateral leukocoria, clinically diagnosed as retinoblastoma, followed by enucleation of ...
Joji, A, Ravikumar, HN, Santosh, KV, Vani, R   +3 more
core   +1 more source

Divergence in cis-regulatory sequences surrounding the opsin gene arrays of African cichlid fishes

BMC Evolutionary Biology, 2011
Background Divergence within cis-regulatory sequences may contribute to the adaptive evolution of gene expression, but functional alleles in these regions are difficult to identify without abundant genomic resources.
Streelman J Todd, Loh Yong-Hwee E, Engel Samuel D, Schulte Jane, Naseer Zan, Smith Daniel, O'Quin Kelly E, Boore Jeffrey L, Carleton Karen L   +8 more
doaj   +1 more source

RH1 sequences & species tree from Convergent evolutionary shifts in rhodopsin retinal release explain shared opsin repertoires in monotremes and crocodilians

, 2023
Jinqu Guo, Hai Chi, Linghan Zhang, Shengjing Song, Stephen J. Rossiter, Yang Liu   +5 more
openalex   +1 more source

Diversity, distribution, and expression of opsin genes in freshwater lakes [PDF]

, 2023
Shaomei He, Alexandra M. Linz, Sarah Stevens, Patricia Q. Tran, Francisco Moya‐Flores, Ben O. Oyserman, Jeffrey R. Dwulit‐Smith, Katrina T. Forest, Katherine D. McMahon   +8 more
openalex   +1 more source

The Evolution of Senses: My Research Journey into the Nervous System of Cnidaria [PDF]

, 2017
Our understanding of the evolutionary history of animals is improving, but knowledge of the ancient sensory systems that early animals used to interact with their environments is still largely unknown.
Hartley, Molly
core   +2 more sources

RT-qPCR reveals opsin gene upregulation associated with age and sex in guppies (Poecilia reticulata) - a species with color-based sexual selection and 11 visual-opsin genes

BMC Evolutionary Biology, 2011
Background PCR-based surveys have shown that guppies (Poecilia reticulata) have an unusually large visual-opsin gene repertoire. This has led to speculation that opsin duplication and divergence has enhanced the evolution of elaborate male coloration ...
Taylor John S, Laver Christopher RJ
doaj   +1 more source

Crustacean conundrums: a review of opsin diversity and evolution [PDF]

, 2022
Sitara Palecanda, Tom Iwanicki, Mireille Steck, Megan L. Porter   +3 more
openalex   +1 more source

Multifunctional opsins [PDF]

Nature Reviews Neuroscience, 2020
openaire   +2 more sources

Structural but Not Functional Alterations in Cones in the Absence of the Retinal Disease Protein Retinitis Pigmentosa 2 (RP2) in a Cone-Only Retina

Frontiers in Genetics, 2019
X-linked retinitis pigmentosa 2 (XLRP2) patients and Rp2null mice exhibit severe cone photoreceptor degeneration. However, due to the paucity of cones in mammalian model systems, it is not clear how cones respond to the loss of RP2. Here we have used the
Linjing Li, Kollu N. Rao, Hemant Khanna
doaj   +1 more source