Results 61 to 70 of about 28,928 (224)
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Genome biology, 2005 The photosensitive molecule rhodopsin and its relatives consist of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal. Opsins, which are G-protein-coupled receptors (GPCRs), are found in animals, and more than a thousand have been identified so far.
openaire +2 more sources
BiP prevents rod opsin aggregation [PDF]
, 2012 Mutations in rod opsin—the light-sensitive protein of rod cells—cause retinitis pigmentosa. Many rod opsin mutations lead to protein misfolding, and therefore it is impor¬tant to understand the role of molecular chaperones in rod opsin biogenesis.
Kanuga, N. +7 more
core +1 more source
Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin
Scientific Reports, 2021 Mutations in the G protein-coupled receptor (GPCR) rhodopsin are a common cause of autosomal dominant retinitis pigmentosa, a blinding disease. Rhodopsin self-associates in the membrane, and the purified monomeric apo-protein opsin dimerizes in vitro as ...
George Khelashvili +11 more
doaj +1 more source
Laser &Photonics Reviews, EarlyView.Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo +20 more
wiley +1 more source
, 2016 Multiple sequence COBALT alignment of putative Odonata and Ephemeroptera opsin protein sequences including homologous opsin sequences from mollusks (outgroup) combined with opsins identified in (Futahashi et al. 2015)
Jensen, Nicholas O. +17 more
core +1 more source
PLoS ONE, 2012 Examples of direct differentiation by defined transcription factors have been provided for beta-cells, cardiomyocytes and neurons. In the human visual system, there are four kinds of photoreceptors in the retina.
Yuko Seko +8 more
doaj +1 more source
Unique Temporal Expression of Triplicated Long-Wavelength Opsins in Developing Butterfly Eyes
Frontiers in Neural Circuits, 2017 Following gene duplication events, the expression patterns of the resulting gene copies can often diverge both spatially and temporally. Here we report on gene duplicates that are expressed in distinct but overlapping patterns, and which exhibit ...
Kentaro Arikawa +3 more
doaj +1 more source
Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning
Scientific Reports, 2021 Visual input to primary visual cortex (V1) depends on highly adaptive filtering in the retina. In turn, isolation of V1 computations requires experimental control of retinal adaptation to infer its spatio-temporal-chromatic output.
I. Rhim, G. Coello-Reyes, I. Nauhaus
doaj +1 more source