Results 41 to 50 of about 28,928 (224)
Optogenetics: Tools for Controlling Brain Cells with Light [PDF]
Molecular Frontiers Journal, 2019 The brain is made out of an incredible diversity of cells called neurons, which have different shapes, are made of different molecules, and that change in different ways in diseases.
Edward S. Boyden
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IEEE AccessAtmospheric turbulence degrades long-range electro-optical (EO) imagery with geometric warping, blur, and temporal jitter. We present a CPU-only, registration-free, tile-wise multi-frame fusion operator specifically tailored for embedded mission systems ...
Zuhal Hancer +2 more
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The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice
Journal of Ophthalmology, 2017 The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or ...
Hua Zhang +9 more
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Genome Biology and EvolutionAbstract In this study, we explored the diversity and evolution of opsins using meta-omic data from the Tara Oceans and Tara Polar Circle expeditions, one of the largest marine datasets available. By using sequence similarity methods and phylogenetic analyses, we identified opsins across the different metazoan groups.
Giacinto De Vivo +3 more
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Molecular evolution and expression of opsin genes in Hydra vulgaris
BMC Genomics, 2019 Background The evolution of opsin genes is of great interest because it can provide insight into the evolution of light detection and vision. An interesting group in which to study opsins is Cnidaria because it is a basal phylum sister to Bilateria with ...
Aide Macias-Muñoz +2 more
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Gene conversion and purifying selection shape nucleotide variation in gibbon L/M opsin genes
BMC Evolutionary Biology, 2011 Background Routine trichromatic color vision is a characteristic feature of catarrhines (humans, apes and Old World monkeys). This is enabled by L and M opsin genes arrayed on the X chromosome and an autosomal S opsin gene.
Siriaroonrat Boripat +9 more
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Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
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Analysis of opsin expression intensity across the mouse retina.
, 2020 (A, E, I) Whole mounted C57BL/6 mouse retina stained for M-opsin (green) and S-opsin (blue). (B, F, J) Heatmap displaying the log relative density of pixels that have opsin signal identified in a 25 mm2 region. (A) M-opsin signal.
Elijah Roberts (227911) +3 more
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Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
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Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation
Frontiers in Neuroscience, 2020 Age-related macular degeneration (AMD) is the leading cause of blindness in industrialized countries among people over 60 years. It has multiple triggers and risk factors, but despite intense research efforts, its pathomechanisms are currently not ...
Natalie Wagner +7 more
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