Results 41 to 50 of about 38,225 (233)
Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent [PDF]
, 2020 Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening.
Armstrong, Lyle +7 more
core +2 more sources
IEEE AccessAtmospheric turbulence degrades long-range electro-optical (EO) imagery with geometric warping, blur, and temporal jitter. We present a CPU-only, registration-free, tile-wise multi-frame fusion operator specifically tailored for embedded mission systems ...
Zuhal Hancer +2 more
doaj +1 more source
A two-step method for identifying photopigment opsin and rhodopsin gene sequences underlying human color vision phenotypes. [PDF]
, 2020 PurposeTo present a detailed, reliable long range-PCR and sequencing (LR-PCR-Seq) procedure to identify human opsin gene sequences for variations in the long wavelength-sensitive (OPN1LW), medium wavelength-sensitive (OPN1MW), short wavelength-sensitive (
Atilano, Shari R +3 more
core +1 more source
The two-photon reversible reaction of the bistable jumping spider rhodopsin-1 [PDF]
, 2019 Bistable opsins are photopigments expressed in both invertebrates and vertebrates. These light-sensitive G-protein-coupled receptors undergo a reversible reaction upon illumination.
Deupi, Xavier +7 more
core +1 more source
The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice
Journal of Ophthalmology, 2017 The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or ...
Hua Zhang +9 more
doaj +1 more source
Red Light Optogenetics in Neuroscience
Frontiers in Cellular Neuroscience, 2022 Optogenetics, a field concentrating on controlling cellular functions by means of light-activated proteins, has shown tremendous potential in neuroscience.
Kimmo Lehtinen +3 more
doaj +1 more source
Novel rodent models for macular research [PDF]
, 2010 Background: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Huber, Gesine +11 more
core +1 more source
Palmitoylation stabilizes unliganded rod opsin [PDF]
Proceedings of the National Academy of Sciences, 2010 S-palmitoylation is a conserved feature in many G protein–coupled receptors (GPCRs) involved in a broad array of signaling processes. The prototypical GPCR, rhodopsin, is S-palmitoylated on two adjacent C-terminal Cys residues at its cytoplasmic surface.
Akiko, Maeda +6 more
openaire +2 more sources
Optogenetics: Tools for Controlling Brain Cells with Light [PDF]
Molecular Frontiers Journal, 2019 The brain is made out of an incredible diversity of cells called neurons, which have different shapes, are made of different molecules, and that change in different ways in diseases.
Edward S. Boyden
doaj +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
core +3 more sources