Results 71 to 80 of about 40,625 (235)
Bleached pigment activates transduction in salamander cones. [PDF]
We have used suction electrode recording together with rapid steps into 0.5 mM IBMX solution to investigate changes in guanylyl cyclase velocity produced by pigment bleaching in isolated cones of the salamander Ambystoma tigrinum.
Cornwall, MC +3 more
core
Evolution![Figure][1] Noctilionoid bats, including the fishing bat shown, have complex mechanisms for eye pigment evolution. PHOTO: CHRISTIAN ZIEGLER/MINDEN PICTURES Opsin genes encode photoreceptor proteins that enable perception of dim light by rod cells and color by cone cells in the eye.
openaire +1 more source
Effect of knocking down the insulin receptor on mouse rod responses. [PDF]
Previous experiments have shown that the insulin receptor (IR) is expressed in mammalian rods and contributes to the protection of photoreceptors during bright-light exposure.
Fain, Gordon L +3 more
core +3 more sources
Ciliary and rhabdomeric photoreceptor cells represent two main lines of photoreceptor-cell evolution in animals. The two cell types coexist in some animals, however how these cells functionally integrate is unknown.
Csaba Verasztó +11 more
doaj +1 more source
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. [PDF]
The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could ...
Angueyra, Juan M +9 more
core +1 more source
Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine [PDF]
Optogenetics is an elegant approach of precisely controlling and monitoring the biological functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution by using optical system and genetic engineering technologies. The
Joshi, Jyotsna +2 more
core +1 more source
Opsin Expression in Human Epidermal Skin [PDF]
AbstractHuman skin is constantly exposed to solar light containing visible and ultraviolet radiation (UVR), a powerful skin carcinogen. UVR elicits cellular responses in epidermal cells via several mechanisms: direct absorption of short‐wavelength UVR photons by DNA, oxidative damage caused by long‐wavelength UVR, and, as we recently demonstrated, via ...
Haltaufderhyde, Kirk +4 more
openaire +2 more sources
Rapid adaptive evolution of colour vision in the threespine stickleback radiation. [PDF]
Vision is a sensory modality of fundamental importance for many animals, aiding in foraging, detection of predators and mate choice. Adaptation to local ambient light conditions is thought to be commonplace, and a match between spectral sensitivity and ...
Heckman, Nancy +4 more
core
Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis. [PDF]
The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood.
Francesca Cordeiro, M +5 more
core +1 more source

