Results 121 to 130 of about 23,776 (285)
Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light
Medicinal Research Reviews, EarlyView.ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva +5 more
wiley +1 more source
Neuromodulation: present and emerging methods. [PDF]
, 2014 Neuromodulation has wide ranging potential applications in replacing impaired neural function (prosthetics), as a novel form of medical treatment (therapy), and as a tool for investigating neurons and neural function (research).
Constandinou, TG +3 more
core +1 more source
Taking Optogenetics into the Human Brain: Opportunities and Challenges in Clinical Trial Design
Open Access Journal of Clinical Trials, 2020 Michael White,1 Michael Mackay,1 Roger G Whittaker1,2 1Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne NE2 4HH, UK; 2Department of Clinical Neurophysiology, Royal Victoria Hospital, Newcastle Upon Tyne NE1 4LP ...
White M, Mackay M, Whittaker RG
doaj
The Last Common Ancestor of Most Bilaterian Animals Possessed at Least Nine Opsins
Genome Biology and Evolution, 2016 The opsin gene family encodes key proteins animals use to sense light and has expanded dramatically as it originated early in animal evolution. Understanding the origins of opsin diversity can offer clues to how separate lineages of animals have ...
MD Ramirez +6 more
semanticscholar +1 more source
Coral reef fish visual adaptations to a changing world
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Coral reef ecosystems show fluctuations in their prevailing light environment in response to both regular (e.g. between seasons) and more prevalent stochastic events (e.g. human‐induced sediment runoff).
Abigail Shaughnessy, Fabio Cortesi
wiley +1 more source
The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation [PDF]
, 2002 Mutations in the photopigment rhodopsin are the major cause of autosomal dominant retinitis pigmentosa. The majority of mutations in rhodopsin lead to misfolding of the protein.
Cheetham, ME +3 more
core
Evolution; international journal of organic evolution, 2018 Light environments critically impact species that rely on vision to survive and reproduce. Animal visual systems must accommodate changes in light that occur from minutes to years, yet the mechanistic basis of their response to spectral (color) changes ...
Alexandrea M Kranz +3 more
semanticscholar +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract The light climate at high latitudes, in particular the extended twilight of winter and the reduced diel variation in light level in midsummer and midwinter, potentially constrains visual function and the synchronisation of temporal organisation in polar species. In this
Nicholas J. C. Tyler +3 more
wiley +1 more source
AAV8 vector induced gliosis following neuronal transgene expression
Frontiers in NeuroscienceIntroductionExpression of light sensitive ion channels by selected neurons has been achieved by viral mediated transduction with gene constructs, but for this to have therapeutic uses, for instance in treating epilepsy, any adverse effects of viral ...
Faye McLeod +8 more
doaj +1 more source
A G Protein-Coupled Receptor Dimerization Interface in Human Cone Opsins.
Biochemistry, 2017 G protein-coupled receptors (GPCRs) detect a wide variety of physical and chemical signals and transmit that information across the cellular plasma membrane. Dimerization is a proposed modulator of GPCR signaling, but the structure and stability of class
B. Jastrzebska +8 more
semanticscholar +1 more source