Results 11 to 20 of about 8,266,744 (203)

CEACAM3—A Prim(at)e Invention for Opsonin-Independent Phagocytosis of Bacteria

Frontiers in Immunology, 2020
Phagocytosis is one of the key innate defense mechanisms executed by specialized cells in multicellular animals. Recent evidence suggests that a particular phagocytic receptor expressed by human polymorphonuclear granulocytes, the carcinoembryonic ...
Patrizia Bonsignore, Johannes W. P. Kuiper, Jonas Adrian, Griseldis Goob, Christof R. Hauck, Christof R. Hauck   +5 more
doaj   +3 more sources

Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles.

ACS Nano, 2023
The therapeutic efficacy and adverse impacts of nanoparticles (NPs) are strongly dependent on their systemic circulation time. The corona proteins adsorbed on the NPs determine their plasma half-lives, and hence, it is crucial to identify the proteins ...
C. Marques, M. Hajipour, Célia Marets, A. Oudot, Reihaneh Safavi-Sohi, M. Guillemin, G. Borchard, O. Jordan, Lucien Saviot, L. Maurizi   +9 more
semanticscholar   +3 more sources

The antibody-peptide fusion protein, AT-02, is an effective opsonin with pan-amyloid reactivity. [PDF]

NPJ Drug Discov
In systemic amyloidosis, the progressive accumulation of amyloid fibrils along with extracellular matrix components causes organ dysfunction, reduced quality of life, and is often fatal.
Wall JS, Williams AD, Balachandran M, Hancock TJ, Richey T, Stuckey AC, Macy S, Wooliver C, Martin EB, Jackson JW, Heidel RE, Guthrie S, Klein ML, Angell N, Kennel SJ, Foster JS.   +15 more
europepmc   +3 more sources

Human mannose-binding protein functions as an opsonin for influenza A viruses. [PDF]

Journal of Clinical Investigation, 1993
Influenza A viruses (IAVs) cause substantial morbidity and mortality in yearly epidemics, which result from the ability of the virus to alter the antigenicity of its envelope proteins. Despite the rapid replication of this virus and its ability to infect a wide variety of cell types, viremia is rare and the infection is generally limited to the upper ...
K. Hartshorn, K. N. Sastry, M. White, E. Anders, M. Super, R. A. Ezekowitz, Alfred I. Tauber   +6 more
semanticscholar   +3 more sources

Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1

Scientific Reports, 2023
The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells.
Elena Boero, Ronald D. Gorham, Emmet A. Francis, Jonathan Brand, Lay Heng Teng, Dennis J. Doorduijn, Maartje Ruyken, Remy M. Muts, Christian Lehmann, Admar Verschoor, Kok P. M. van Kessel, Volkmar Heinrich, Suzan H. M. Rooijakkers   +12 more
doaj   +2 more sources

Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis [PDF]

Translational Psychiatry, 2020
Potentially neurotoxic systems involved in traumatic and degenerative diseases of the brain were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs) and neuron-derived exosomes (NDEs) were immunoprecipitated from plasma of ten untreated first ...
E. Goetzl, V. Srihari, S. Guloksuz, M. Ferrara, C. Tek, G. Heninger   +5 more
semanticscholar   +3 more sources

Phylogenetic lineage and pilus protein Spb1/SAN1518 affect opsonin-independent phagocytosis and intracellular survival of Group B Streptococcus [PDF]

Microbes and Infection, 2011
Opsonin-independent phagocytosis of Group B Streptococcus (GBS) is important in defense against neonatal GBS infections. A recent study indicated a role for GBS pilus in macrophage phagocytosis (Maisey et al Faseb J 22 2008 1715-24).
Debasish Chattopadhyay, Adderson, Elisabeth E, Ulett, Glen C., Glen C. Ulett, Richard I. Webb, Carey, Alison J., Bohnsack, John F, Elisabeth E. Adderson, Layton, James R, Wang, Yan, Webb, Richard I., Adderson, Elisabeth E., Webb, Richard I, Caliot, Elise, Bohnsack, John F., Elise Caliot, Yan Wang, John F. Bohnsack, Ulett, Glen C, Chattopadhyay, Debasish, Layton, James R., Carey, Alison J, Alison J. Carey, James R. Layton   +23 more
core   +7 more sources

Expression of Ciona intestinalis variable region-containing chitin-binding proteins during development of the gastrointestinal tract and their role in host-microbe interactions.

PLoS ONE, 2014
Variable region-containing chitin-binding proteins (VCBPs) are secreted, immune-type molecules that have been described in both amphioxus, a cephalochordate, and sea squirt, Ciona intestinalis, a urochordate.
Assunta Liberti, Daniela Melillo, Ivana Zucchetti, Lenina Natale, Larry J Dishaw, Gary W Litman, Rosaria De Santis, Maria Rosaria Pinto   +7 more
doaj   +2 more sources

Pathogenic implications for autoantibodies against C-reactive protein and other acute phase proteins. [PDF]

Clinica chimica acta; international journal of clinical chemistry, 2007
Systemic lupus erythematosus (SLE) is a systemic rheumatic disease characterized clinically by multiorgan involvement and serologically by the occurrence of antinuclear antibodies.
C. Sjöwall, J. Wetterö
semanticscholar   +2 more sources

ROLE OF IMMUNOGLOBULIN G (IgG) FROM THE INDUCTION OF Escherichia coli PILI ADHESION PROTEIN ISOLATED FROM INFERTILE MALE SEMEN WITH 32.2 KDA MOLECULAR WEIGHT AS OPSONIN AND ANTI-ADHESION AN IN VITRO Escherichia coli INFECTION

Folia Medica Indonesiana, 2017
Escherichia coli (E. coli), a major cause of male genital tract infections, is asymptomatic and may result in male infertility. We have succeeded in isolating and characterizing proteins of E.
Sukarjati Sukarjati, Susie Amilah
doaj   +3 more sources