Complement and transplant-associated thrombotic microangiopathy: Current and future approaches. [PDF]
HemasphereHemaSphere, Volume 10, Issue 4, April 2026.
Cugno M, Onida F, Lämmle B.
europepmc +2 more sources
Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface [PDF]
Nature Communications, 2020 AbstractNanomaterials in the blood must mitigate the immune response to have a prolonged vascular residency in vivo. The composition of the protein corona that forms at the nano-biointerface may be directing this, however, the possible correlation of corona composition with blood residency is currently unknown.
Srinivas Abbina +7 more
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Opsonins and Dysopsonins of Nanoparticles: Facts, Concepts, and Methodological Guidelines
Frontiers in Immunology, 2020 Understanding the effects mediated by a set of nanoparticle (NP)-bound host biomolecules, often indicated with the umbrella term of NP corona, is essential in nanomedicine, nanopharmacology, and nanotoxicology.
Emanuele Papini +4 more
doaj +1 more source
Complement evasion factor (CEF), a novel immune evasion factor of Streptococcus pyogenes
Virulence, 2022 Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S.
Haniyeh Aghababa +5 more
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Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D [PDF]
Proceedings of the National Academy of Sciences, 1999 Surfactant protein D (SP-D) is an oligomeric C type lectin that promotes phagocytosis by binding to microbial surface carbohydrates. A 340-kDa glycoprotein (gp-340) has been shown to bind SP-D in the presence of calcium but does so independently of carbohydrate recognition.
Holmskov, U +9 more
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Use of monoclonal antibodies to protein F of Pseudomonas aeruginosa as opsonins for phagocytosis by macrophages [PDF]
Infection and Immunity, 1987 Five protein F-specific monoclonal antibodies were found to opsonize Pseudomonas aeruginosa for complement-independent phagocytosis by unelicited mouse peritoneal macrophages, mouse macrophage cell line P388D1, and human monocyte-derived macrophages. Immunoglobulin G1 antibodies seemed to be a preferred isotype.
J L, Battershill +2 more
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Frontiers in Cellular Neuroscience, 2022 Galectin-3 (Gal-3; formally named MAC-2) is a β-galactoside-binding lectin. Various cell types produce Gal-3 under either normal conditions and/or pathological conditions. Gal-3 can be present in cells' nuclei and cytoplasm, secreted from producing cells,
Shlomo Rotshenker
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A C1q domain containing protein from scallop Chlamys farreri serving as pattern recognition receptor with heat-aggregated IgG binding activity. [PDF]
PLoS ONE, 2012 BACKGROUND: The C1q domain containing (C1qDC) proteins refer to a family of all proteins that contain the globular C1q (gC1q) domain, and participate in a series of immune responses depending on their gC1q domains to bind a variety of self and non-self ...
Leilei Wang +5 more
doaj +1 more source
Phagocytosis of Viable Candida albicans by Alveolar Macrophages: Lack of Opsonin Function of Surfactant Protein A [PDF]
Journal of Infectious Diseases, 1997 Surfactant protein A (SP-A) contributes to host defense by opsonizing microbial organisms for phagocytosis by alveolar macrophages (AM). The role of SP-A as opsonin for phagocytosis of Candida albicans was analyzed. AM in suspension exhibited no phagocytosis of nonopsonized yeast. This was not increased by SP-A, whether provided for preincubation of AM
S, Rosseau +3 more
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Scientific Reports, 2023 The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells.
Elena Boero +12 more
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