CEACAM3—A Prim(at)e Invention for Opsonin-Independent Phagocytosis of Bacteria
Frontiers in Immunology, 2020 Phagocytosis is one of the key innate defense mechanisms executed by specialized cells in multicellular animals. Recent evidence suggests that a particular phagocytic receptor expressed by human polymorphonuclear granulocytes, the carcinoembryonic ...
Patrizia Bonsignore +5 more
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Human Opsonins Induced during Meningococcal Disease Recognize Transferrin Binding Protein Complexes [PDF]
Infection and Immunity, 1999 ABSTRACT Patient serum opsonins against transferrin binding protein A+B (TbpA+B) complexes from two Neisseria meningitidis strains (K454 and B16B6, with 85- and 68-kDa TbpB, respectively) were quantified by a functional phagocytosis and oxidative burst assay.
A K, Lehmann +5 more
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The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria. [PDF]
PLoS ONE, 2012 BACKGROUND: CEACAM3 is a granulocyte receptor mediating the opsonin-independent recognition and phagocytosis of human-restricted CEACAM-binding bacteria.
Stefan Pils +5 more
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Multiscale Biofluidic and Nanobiotechnology Approaches for Treating Sepsis in Extracorporeal Circuits [PDF]
, 2020 Infectious diseases and their pandemics periodically attract public interests due to difficulty in treating the patients and the consequent high mortality.
Kang, Joo H.
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Function of the lipopolysaccharide‐binding protein of Periplaneta americana as an opsonin
FEBS Letters, 1992 Previously, we reported the purification of an LPS‐binding protein from the hemolymph of the American cockroach that was specific for E. coli LPS. In this study we found that this protein participated in the clearance of E. coil cells injected into the abdominal cavity of the cockroach, and that hemocytes ingested E.
Jomori, Takahito, Natori, Shunji
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Biological significance of C-reactive protein, the ancient acute phase functionary
Frontiers in Immunology, 2023 C-reactive protein (CRP) is one of the major members of the family of acute phase proteins (APP). Interest in this CRP was the result of a seminal discovery of its pattern of response to pneumococcal infection in humans.
Shelley Bhattacharya, Chayan Munshi
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PLoS ONE, 2012 Control of macrophage capacity for apoptotic cell clearance by soluble mediators such as cytokines, prostaglandins and lipoxins, serum proteins, and glucocorticoids may critically determine the rate at which inflammation resolves.
Simon P Hart +3 more
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Frontiers in Immunology, 2023 IntroductionSystemic amyloidosis is a progressive disorder characterized by the extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and tissues.
James S. Foster +11 more
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C-type lectin in Chlamys farreri (CfLec-1) mediating immune recognition and opsonization. [PDF]
PLoS ONE, 2011 BACKGROUND: C-type lectins are a superfamily of Ca(2+) dependent carbohydrate-recognition proteins that play significant diverse roles in nonself-recognition and clearance of invaders.
Jialong Yang +5 more
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Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]
, 2010 Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M. +7 more
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