The Journal of Immunology, 1987 Although many functions of phagocytes are known to be regulated by guanosine triphosphate (GTP)-binding proteins, phagocytosis itself has not been considered one of these. However, previous studies have examined only unstimulated neutrophil phagocytosis.
Eric J. Brown, A. Newell, H. Gresham
semanticscholar +3 more sources
The role of neisserial Opa proteins in interactions with host cells.
Trends in Microbiology, 1998 Pathogenic Neisseria spp. possess a repertoire of phase-variable Opa proteins that mediate various pathogen--host cell interactions, including bacterial engulfment by epithelial cells and opsonin-independent phagocytosis by professional phagocytes ...
C. Dehio, S. Gray-Owen, Thomas F. Meyer
semanticscholar +2 more sources
Competitive adsorption of serum proteins at microparticles affects phagocytosis by dendritic cells.
Biomaterials, 2003 Serum protein adsorption to the surface of particulate synthetic drug carrier systems has a major influence on their uptake by phagocytes. The influence of α2-human serum glycoprotein ({alpha}2GP) on the phagocytosis of various surface modified ...
L. Thiele +4 more
semanticscholar +2 more sources
Basal activation of ERK1/2 blunts the antimicrobial activity of neutrophils from old hosts against antibody-opsonized Streptococcus pneumoniae. [PDF]
J Leukoc BiolAge-related decline in neutrophil function reduces vaccine protection against Streptococcus pneumoniae. In vaccinated hosts, neutrophil activation via complement and Fcγ receptors mediates bacterial uptake and killing.
Simmons SR, Rivera A, Bou Ghanem EN.
europepmc +2 more sources
Opsonin-Deficient Nucleoproteic Corona Endows UnPEGylated Liposomes with Stealth Properties In Vivo
, 2022 For several decades, surface grafted polyethylene glycol (PEG) has been a go-to strategy for preserving the synthetic identity of liposomes in physiological milieu and preventing clearance by immune cells.
Riccardo Zenezini Chiozzi (8866901) +18 more
core +2 more sources
An Insect Multiligand Recognition Protein Functions as an Opsonin for the Phagocytosis of Microorganisms [PDF]
Journal of Biological Chemistry, 2010 We characterize a novel pathogen recognition protein obtained from the lepidopteran Galleria mellonella. This protein recognizes Escherichia coli, Micrococcus luteus, and Candida albicans via specific binding to lipopolysaccharides, lipoteichoic acid, and beta-1,3-glucan, respectively. As a multiligand receptor capable of coping with a broad variety of
Chong Han, Kim +6 more
openaire +2 more sources
Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D [PDF]
Proceedings of the National Academy of Sciences, 1999 Surfactant protein D (SP-D) is an oligomeric C type lectin that promotes phagocytosis by binding to microbial surface carbohydrates. A 340-kDa glycoprotein (gp-340) has been shown to bind SP-D in the presence of calcium but does so independently of carbohydrate recognition.
Holmskov, U +9 more
openaire +3 more sources
Use of monoclonal antibodies to protein F of Pseudomonas aeruginosa as opsonins for phagocytosis by macrophages [PDF]
Infection and Immunity, 1987 Five protein F-specific monoclonal antibodies were found to opsonize Pseudomonas aeruginosa for complement-independent phagocytosis by unelicited mouse peritoneal macrophages, mouse macrophage cell line P388D1, and human monocyte-derived macrophages. Immunoglobulin G1 antibodies seemed to be a preferred isotype.
J L, Battershill +2 more
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Phagocytosis of Viable Candida albicans by Alveolar Macrophages: Lack of Opsonin Function of Surfactant Protein A [PDF]
Journal of Infectious Diseases, 1997 Surfactant protein A (SP-A) contributes to host defense by opsonizing microbial organisms for phagocytosis by alveolar macrophages (AM). The role of SP-A as opsonin for phagocytosis of Candida albicans was analyzed. AM in suspension exhibited no phagocytosis of nonopsonized yeast. This was not increased by SP-A, whether provided for preincubation of AM
S, Rosseau +3 more
openaire +2 more sources
Opsonin-Deficient Nucleoproteic Corona Endows UnPEGylated Liposomes with Stealth Properties In Vivo
, 2022 For several decades, surface grafted polyethylene glycol (PEG) has been a go-to strategy for preserving the synthetic identity of liposomes in physiological milieu and preventing clearance by immune cells.
Riccardo Zenezini Chiozzi (8866901) +37 more
core +1 more source