Results 61 to 70 of about 90,641 (320)

Establishing induced pluripotent stem cell lines from two dominant optic atrophy patients with distinct OPA1 mutations and clinical pathologies

Frontiers in Genetics, 2023
Dominant optic atrophy (DOA) is an inherited disease that leads to the loss of retinal ganglion cells (RGCs), the projection neurons that relay visual information from the retina to the brain through the optic nerve.
Katherine A. Pohl, Katherine A. Pohl, Xiangmei Zhang, Anh H. Pham, Jane W. Chan, Alfredo A. Sadun, Xian-Jie Yang, Xian-Jie Yang   +7 more
doaj   +1 more source

Emerging functions of mammalian mitochondrial fusion and fission [PDF]

, 2005
Mitochondria provide a myriad of services to the cell, including energy production, calcium buffering and regulation of apoptosis. How these diverse functions are coordinated among the hundreds of mitochondria in a given cell is largely unknown, but is ...
Chan, David C., Chen, Hsiuchen
core   +1 more source

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]

, 2015
Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E, Biscaro, A, Cama, Elona, Caporali, L, Carelli, V., La Morgia, C, Liguori, R, Magnavita, V, Monteleone, A, Rossi, R, Santarelli, Rosamaria, Scimemi, Pietro, Valentino, Ml   +12 more
core   +3 more sources

A case of a young patient with progressive vision loss: An atypical presentation of the rare Wolfram Syndrome in a Middle Eastern individual

American Journal of Ophthalmology Case Reports
Purpose: To describe an atypical presentation of a rare disease in a young middle eastern woman with a relatively adult-onset type 1 diabetes mellitus, bilateral optic atrophy and progressive decreased vision diagnosed as the Wolfram disease. Observation:
Meishar Meisel, Eran Berkowitz, Dana Irge, Beatrice Tiosano, Anat Kesler   +4 more
doaj   +1 more source

Nationwide usage of ethambutol and incidence and screening practices of optic neuropathy

Frontiers in Pharmacology
IntroductionEthambutol, a key anti-tuberculosis medication, is associated with optic neuropathy, which can lead to significant vision impairment. This population-based cohort study investigated the nationwide usage of ethambutol and the incidence and ...
Jiyeong Kim, Hyeon Yoon Kwon, Seong Joon Ahn   +2 more
doaj   +1 more source

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. [PDF]

, 2019
BACKGROUND:Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss.
Aktas, Orhan, Albrecht, Philipp, Balk, Lisanne J, Cordano, Christian, Cruz-Herranz, Andrés, Dietrich, Michael, Fischer, Dietmar, Green, Ari J, Hallenberger, Angelika, Hartung, Hans-Peter, Hecker, Christina, Hilla, Alexander M, Ingwersen, Jens, Issberner, Andrea, Lehmann-Horn, Klaus, Levin, Marc H, von Gall, Charlotte, Yiu, Hao H, Zamvil, Scott S   +18 more
core   +1 more source

Retinal Vessel Density in Optical Coherence Tomography Angiography in Optic Atrophy after Nonarteritic Anterior Ischemic Optic Neuropathy

Journal of Ophthalmology, 2017
Aims. To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between normal and optic atrophy after nonarteritic anterior ischemic optic neuropathy (NAION) subjects. Design.
Chun-Hsiu Liu, Ling-Yuh Kao, Ming-Hui Sun, Wei-Chi Wu, Henry Shen-Lih Chen   +4 more
doaj   +1 more source

Fundus changes in high myopic Kashmiri population

Asian Journal of Medical Sciences, 2021
Background: High myopia (defined as myopia of -6D or more) is one of the main causes of visual impairment worldwide. High myopia is always accompanied by pathological structural changes such as axial elongation, posterior staphyloma, lacquer crack ...
Nazia Anjum , Numrah Muqsit , Junaid S Wani   +2 more
doaj   +1 more source

Functional correlates of optic flow motion processing in Parkinson’s disease [PDF]

, 2014
The visual input created by the relative motion between an individual and the environment, also called optic flow, influences the sense of self-motion, postural orientation, veering of gait, and visuospatial cognition.
Cronin-Golomb, Alice, Norton, Daniel J., Putcha, Deepti, Rosen, Maya L., Ross, Robert S., Somers, David C., Stern, Chantal E.   +6 more
core   +5 more sources

Morphological and functional characteristics of an eye in vibration disease patients

Oftalʹmologiâ, 2015
Aim: To analyze ocular fundus photos and visual field test findings in vibration disease patients depending on highfrequencyexposition.Methods: 62 vibration disease patients aged 40‑65 (55.69±0.7 years on average) were examined. The patients were divided
S. S. Malysheva, S. A. Petrov
doaj   +3 more sources