Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion. [PDF]
Radiol Case Rep, 2019 Malignant optic glioma presents a clinical and diagnostic challenge, as early imaging findings overlap with other more common causes of optic nerve enhancement and enlargement, potentially leading to delay in diagnosis.
Kalnins A +5 more
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Asthma-mediated control of optic glioma growth via T cell-microglia interactions: A mathematical model. [PDF]
NPJ Syst Biol ApplOptic glioma, a slow-growing tumor, is associated with Neurofibromatosis type 1 (NF1) mutations and increased midkine (MDK) production. A connection between asthma and optic glioma has previously been observed, but the mechanisms are unclear.
Lee D, Lawler S, Kim Y.
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Diffuse midline glioma, H3 K27-altered, forming a suprasellar mass: A case report [PDF]
Radiol Case RepDiffuse midline glioma, H3 K27-altered (DMG), is an extremely aggressive tumor that mainly arises in midline structures such as the thalamus, brainstem, and spinal cord in children and young adults.
Nakazato R +11 more
europepmc +2 more sources
Brain injury drives optic glioma formation through neuron-glia signaling. [PDF]
Acta Neuropathol CommunTissue injury and tumorigenesis share many cellular and molecular features, including immune cell (T cells, monocytes) infiltration and inflammatory factor (cytokines, chemokines) elaboration.
Chatterjee J +11 more
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Neurologijos seminarai, 2023 Optic nerve glioma (ONG) is usually a low-grade tumor of the optic nerve. ONG can affect not only the optic nerve, but also the optic nerve chiasma and optic nerve tract.
U. Masilionytė +3 more
doaj +3 more sources
Magnetic resonance imaging characteristics of glioblastoma of the optic pathway during adulthood
Radiology Case Reports, 2023 Glioma has been previously known as the most common adult brain tumor. Glioma of the optic pathway is predominated by low-grade neoplasms. High-grade glioma in adults is extremely rare. In this study, we present the case of a 46-year-old male patient who
Le Thanh Dung, MD +6 more
doaj +1 more source
Synergistic antitumor effect of temozolomide and perampanel in pediatric glioma: a case report and in vitro validation using patient-derived glioma sphere cells. [PDF]
Acta Neuropathol CommunPediatric low-grade gliomas are the most common central nervous system tumors; however, therapeutic options remain limited for tumors involving critical structures, such as the optic pathway, particularly when malignant transformation occurs ...
Omachi T +11 more
europepmc +2 more sources
Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia
Nature Communications, 2021 Clinical studies have suggested a reduced incidence of brain tumors, including optic gliomas, in children with asthma. Here, in a mouse model of Neurofibromatosis type 1 associated low grade optic glioma, the authors show that experimental asthma ...
Jit Chatterjee +9 more
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Frontiers in Oncology, 2021 Optic nerve hemangioblastoma is a very rare benign tumor with only 39 reported cases by now. It appears to be hyperintense on T2-weighted images with a significant enhancement on contrast scans, which are similar to glioma and meningioma. Due to the lack
Meihan Duan +5 more
doaj +1 more source
Malignant optic nerve glioma in a young woman with 7 year follow up without recurrence
American Journal of Ophthalmology Case Reports, 2020 Purpose: To report diagnostic and management challenges of a case of WHO Grade III glioma of the optic nerve occurring in an unusually young patient with more than 7 years of survival without recurrence.
Chris R. Alabiad +4 more
doaj +1 more source